Essential elements in depression and anxiety. Part II

Katarzyna Mlyniec*, Magdalena Gawel, Urszula Doboszewska, Gabriela Starowicz, Karolina Pytka, Claire Davies, Boguslawa Budziszewska

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

In this paper we continue to discuss the involvement of essential elements in depression and anxiety, and the possible mechanisms that link elements to the neurobiology underlying depression/anxiety. The present paper is focused on copper, selenium, manganese, iodine and vanadium. Different aspects of relationship between elements and depression or anxiety are reviewed, e.g. the association of the amount of an element in a diet or the serum level of an element and depressive or anxiety-like symptoms. Moreover, the relation of selected elements to the pathophysiology of depression or anxiety is discussed in the context of enzymes which require these elements as co-factors and are involved in the underlying pathophysiology of these disorders. (C) 2014 Institute of Pharmacology, Polish Academy of Sciences. Published by Elsevier Urban & Partner Sp. Z o.o. All rights reserved.

Original languageEnglish
Pages (from-to)187-194
Number of pages8
JournalPharmacological reports
Volume67
Issue number2
Early online date27 Sep 2014
DOIs
Publication statusPublished - Apr 2015

Keywords

  • Depression
  • Copper
  • Selenium
  • Iodine
  • Trace elements
  • CENTRAL-NERVOUS-SYSTEM
  • L-THYROXINE TREATMENT
  • SERUM TRACE-ELEMENTS
  • QUALITY-OF-LIFE
  • SUBCLINICAL HYPOTHYROIDISM
  • MAJOR DEPRESSION
  • MANGANESE NEUROTOXICITY
  • OXIDATIVE STRESS
  • MOOD DISORDERS
  • POSTPARTUM DEPRESSION

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