Estrogen dependent signaling in reproductive tissues - a role for estrogen receptors and estrogen related receptors

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

Estrogens play a fundamental role in the development and normal physiological function of multiple tissue systems and have been implicated in the ontogeny of cancers. The biological effects of estrogens are classically mediated via interaction with cognate nuclear receptors. The relative expression of ER subtypes/variants varies between cells within different tissues and this alters the response to natural and synthetic ligands. This review focuses on the role of estrogen and estrogen related receptors in reproductive tissues.
Original languageEnglish
Pages (from-to)361-72
Number of pages12
JournalMolecular and Cellular Endocrinology
Volume348
Issue number2
DOIs
Publication statusPublished - 2012

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