Projects per year
Abstract
It is a challenge to find participants for Alzheimer's disease (AD) prevention trials within a short period of time. The European Prevention of Alzheimer's Dementia Registry (EPAD) aims to facilitate recruitment by preselecting subjects from ongoing cohort studies. This article introduces this novel approach.
Methods
A virtual registry, with access to risk factors and biomarkers for AD through minimal data sets of ongoing cohort studies, was set up.
Results
To date, ten cohorts have been included in the EPAD. Around 2500 participants have been selected, using variables associated with the risk for AD. Of these, 15% were already recruited in the EPAD longitudinal cohort study, which serves as a trial readiness cohort.
Discussion
This study demonstrates that a virtual registry can be used for the preselection of participants for AD studies.
Original language | English |
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Pages (from-to) | 837-842 |
Number of pages | 6 |
Journal | Alzheimer's & Dementia: The Journal of the Alzheimer's Association |
Volume | 14 |
Issue number | 6 |
Early online date | 28 Mar 2018 |
DOIs | |
Publication status | Published - 1 Jun 2018 |
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Dive into the research topics of 'European Prevention of Alzheimer's Dementia Registry: Recruitment and prescreening approach for a longitudinal cohort and prevention trials'. Together they form a unique fingerprint.Projects
- 3 Finished
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Stratifying Resilience and Depression Longitudinally
McIntosh, A. (Principal Investigator), Deary, I. (Co-investigator), Evans, K. (Co-investigator), Haley, C. (Co-investigator) & Porteous, D. (Co-investigator)
1/01/15 → 30/06/21
Project: Research
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Generation Scotland
Porteous, D. (Principal Investigator)
UK central government bodies/local authorities, health and hospital authorities
1/04/11 → 31/03/14
Project: Research
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Genetic Health 21st Century
Porteous, D. (Principal Investigator), Laurie, G. (Co-investigator) & Tait, J. (Co-investigator)
UK central government bodies/local authorities, health and hospital authorities
1/10/03 → 31/08/07
Project: Research