Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models

Medicine and Dentistry

• Therapeutic Procedure 100%
• Human Insulin 100%
• Cell Culture 100%
• Evaluation Study 100%
• Mutant 81%
• Insulin Receptor 54%
• Insulin 45%
• Antibody 36%
• Insulin Resistance 27%
• Adipocyte 18%
• 3T3-L1 18%
• Receptor 18%
• Antibody Response 9%
• Loss of Function Mutation 9%
• Species 9%
• Autophosphorylation 9%
• Agonist 9%
• Insulin Response 9%
• Mitogen Activated Protein Kinase 3 9%
• Transgene 9%
• Combination Therapy 9%
• Targeted Therapy 9%
• Epitope 9%
• Short Hairpin RNA 9%
• Phosphorylation 9%
• Mortality 9%

Biochemistry, Genetics and Molecular Biology

• Antibody 100%
• Insulin 100%
• Electric Potential 100%
• Cell Culture 100%
• Insulin Receptor 100%
• Mutant 81%
• Insulin Resistance 27%
• Mouse 18%
• 3T3-L1 18%
• Monoclonal Antibody 18%
• Adipocyte 18%
• Mutation 9%
• Transgene 9%
• Autophosphorylation 9%
• Antibody Response 9%
• Species 9%
• Mortality 9%
• Phosphorylation 9%
• Loss of Function Mutation 9%
• Insulin Response 9%
• Agonist 9%

Immunology and Microbiology

• Cell Culture 100%
• Electric Potential 100%
• Insulin Receptor Antibody 100%
• Mutant 81%
• Insulin Receptor 54%
• Monospecific Antibody 36%
• Insulin Resistance 27%
• Mouse 18%
• Adipocyte 18%
• Antibody Response 9%
• Species 9%
• Autophosphorylation 9%
• Mortality 9%
• Agonist 9%
• Loss of Function Mutation 9%
• Transgene 9%
• Phosphorylation 9%
• Epitope 9%
• Mutation 9%
• Insulin Response 9%