Evaluation of changes in central airway dimensions, lung area and mean lung density at paired inspiratory/expiratory high-resolution computed tomography

Joerg Ederle, CP Heussel, J Hast, B Fischer, EJR van Beek, S Ley, M Thelen, HU Kauczor

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to improve the understanding of interdependencies of dynamic changes in central airway dimensions, lung area and lung density on HRCT. The HRCT scans of 156 patients obtained at full inspiratory and expiratory position were evaluated retrospectively. Patients were divided into four groups according to lung function tests: normal subjects (n=47); obstructive (n=74); restrictive (n=19); or mixed ventilatory impairment (n=16). Mean lung density (MLD) was correlated with cross-sectional area of the lung (CSA(L)), cross-sectional area of the trachea (CSA(T)) and diameter of main-stem bronchi (D-B). The CSA(L) was correlated with CSA(T) and D-B. MLD correlated with CSA(L) in normal subjects (r=-0.66, p

Original languageEnglish
Pages (from-to)2454-2461
Number of pages8
JournalEuropean Radiology
Volume13
Issue number11
DOIs
Publication statusPublished - Nov 2003

Keywords

  • X-ray computed tomography
  • lung
  • densitometry
  • comparative studies
  • ventilation
  • airways dimensions
  • OBSTRUCTIVE PULMONARY-DISEASE
  • THIN-SECTION CT
  • QUANTITATIVE CT
  • FUNCTION TESTS
  • NITRIC-OXIDE
  • CINE-CT
  • EMPHYSEMA
  • DENSITOMETRY
  • ATTENUATION
  • VENTILATION

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