Evaluation of exhaled breath condensate pH as a biomarker for COPD

William MacNee; Stephen I Rennard; John F Hunt; Lisa D Edwards; Bruce E Miller; Nicholas W Locantore; Ruth Tal-Singer

doi:10.1016/j.rmed.2011.02.009

Evaluation of exhaled breath condensate pH as a biomarker for COPD

William MacNee, Stephen I Rennard, John F Hunt, Lisa D Edwards, Bruce E Miller, Nicholas W Locantore, Ruth Tal-Singer

Research output: Contribution to journal › Article › peer-review

Abstract

We assessed the utility of EBC pH as a biomarker in COPD in a large cohort of well-characterised individuals with COPD and control subjects from the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study. We also determined short term reproducibility and the response of EBC to oral prednisolone.

Original language	English
Pages (from-to)	1037-45
Number of pages	9
Journal	American Journal of Respiratory and Critical Care Medicine
Volume	105
Issue number	7
DOIs	https://doi.org/10.1016/j.rmed.2011.02.009
Publication status	Published - 2011

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10.1016/j.rmed.2011.02.009

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title = "Evaluation of exhaled breath condensate pH as a biomarker for COPD",

abstract = "We assessed the utility of EBC pH as a biomarker in COPD in a large cohort of well-characterised individuals with COPD and control subjects from the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study. We also determined short term reproducibility and the response of EBC to oral prednisolone.",

author = "William MacNee and Rennard, {Stephen I} and Hunt, {John F} and Edwards, {Lisa D} and Miller, {Bruce E} and Locantore, {Nicholas W} and Ruth Tal-Singer",

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AU - MacNee, William

AU - Rennard, Stephen I

AU - Hunt, John F

AU - Edwards, Lisa D

AU - Miller, Bruce E

AU - Locantore, Nicholas W

AU - Tal-Singer, Ruth

PY - 2011

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N2 - We assessed the utility of EBC pH as a biomarker in COPD in a large cohort of well-characterised individuals with COPD and control subjects from the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study. We also determined short term reproducibility and the response of EBC to oral prednisolone.

AB - We assessed the utility of EBC pH as a biomarker in COPD in a large cohort of well-characterised individuals with COPD and control subjects from the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study. We also determined short term reproducibility and the response of EBC to oral prednisolone.

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U2 - 10.1016/j.rmed.2011.02.009

DO - 10.1016/j.rmed.2011.02.009

M3 - Article

C2 - 21377342

SN - 1535-4970

VL - 105

SP - 1037

EP - 1045

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

IS - 7

ER -

Evaluation of exhaled breath condensate pH as a biomarker for COPD

Abstract

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