Evidence for the Transmission of Plasmodium vivax in the Republic of the Congo, West Central Africa

Richard Culleton, Mathieu Ndounga, Fadile Yildiz Zeyrek, Cevayir Coban, Prisca Nadine Casimiro, Satoru Takeo, Takafumi Tsuboi, Anjali Yadava, Richard Carter, Kazuyuki Tanabe

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Plasmodium vivax is not thought to be transmitted in western and central Africa, because of the very high prevalence of the red blood cell Duffy-negative phenotype in local populations, a condition which is thought to confer complete resistance against blood infection with P. vivax. There are, however, persistent reports of travelers returning from this region with P. vivax infections. To investigate whether transmission occurs in this region, the presence of antibodies specific to P. vivax preerythrocytic-stage antigens was assessed in individuals from the Republic of the Congo. A total of 55 (13%) of 409 samples tested by enzyme-linked immunosorbent assay had antibodies to P. vivax-specific antigens.

Original languageEnglish
Pages (from-to)1465-1469
Number of pages5
JournalThe Journal of Infectious Diseases
Issue number9
Publication statusPublished - 1 Nov 2009

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