Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes

Earth & Environmental Sciences

• human disease 100%
• genome 70%
• gene 56%
• rodent 39%
• amino acid 11%
• substitution 11%
• pulmonary disease 6%
• rate 5%
• malformation 5%
• etiology 5%
• chromosome 4%
• mutation 4%
• contraction 3%
• brain 3%
• organism 2%

Agriculture & Biology

• human diseases 80%
• mice 43%
• genome 41%
• rats 38%
• rodents 31%
• genes 25%
• hematologic diseases 6%
• microsatellite repeats 6%
• loci 5%
• amino acids 4%
• mutation rate 4%
• respiratory tract diseases 4%
• amino acid substitution 4%
• etiology 4%
• nucleotides 2%
• brain 2%
• chromosomes 2%
• organisms 2%

Medicine & Life Sciences

• Genome 50%
• Genes 30%
• Rodentia 26%
• Trinucleotide Repeats 14%
• Neurological Models 5%
• Trinucleotide Repeat Expansion 5%
• Amino Acids 5%
• Hematologic Diseases 4%
• Human Chromosomes 4%
• Amino Acid Substitution 3%
• Immune System Diseases 3%
• Mutation Rate 3%
• Lung Diseases 3%
• Nucleotides 2%
• Brain 1%
• Therapeutics 0%