Expanding opportunities for mining bioactive chemistry from patents

Christopher Southan

doi:10.1016/j.ddtec.2014.12.001

Expanding opportunities for mining bioactive chemistry from patents

Christopher Southan

Deanery of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Bioactive structures published in medicinal chemistry patents typically exceed those in papers by at least twofold and may precede them by several years. The Big-Bang of open automated extraction since 2012 has contributed to over 15 million patent-derived compounds in PubChem. While mapping between chemical structures, assay results and protein targets from patent documents is challenging, these relationships can be harvested using open tools and are beginning to be curated into databases.

Original language	English
Journal	Drug Discovery Today: Technologies
Early online date	10 Feb 2015
DOIs	https://doi.org/10.1016/j.ddtec.2014.12.001
Publication status	Published - Feb 2015

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10.1016/j.ddtec.2014.12.001

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http://linkinghub.elsevier.com/retrieve/pii/S1740674914000304

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GUIDETOPHARMACOLOGY.ORG - A PEER REVIEWED ONLINE RESOURCE GIVING INFORMATION ON DRUGS AND THEIR TARGETS
Harmar, A.
UK-based charities
1/11/12 → 31/01/14
Project: Research

Cite this

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Expanding opportunities for mining bioactive chemistry from patents

Abstract

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GUIDETOPHARMACOLOGY.ORG - A PEER REVIEWED ONLINE RESOURCE GIVING INFORMATION ON DRUGS AND THEIR TARGETS

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