Expanding opportunities for mining bioactive chemistry from patents

Christopher Southan

Research output: Contribution to journalArticlepeer-review


Bioactive structures published in medicinal chemistry patents typically exceed those in papers by at least twofold and may precede them by several years. The Big-Bang of open automated extraction since 2012 has contributed to over 15 million patent-derived compounds in PubChem. While mapping between chemical structures, assay results and protein targets from patent documents is challenging, these relationships can be harvested using open tools and are beginning to be curated into databases.
Original languageEnglish
JournalDrug Discovery Today: Technologies
Early online date10 Feb 2015
Publication statusPublished - Feb 2015


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