Experimental conditions affect the outcome of Plasmodium falciparum platelet-mediated clumping assays

Mònica Arman, J Alexandra Rowe

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes (IE) is a parasite adhesion phenotype that has been associated with severe malaria in some, but not all, field isolate studies. A variety of experimental conditions have been used to study clumping in vitro, with substantial differences in parasitaemia (Pt), haematocrit (Ht), and time of reaction between studies. It is unknown whether these experimental variables affect the outcome of parasite clumping assays.
Original languageEnglish
Article number243
Number of pages15
JournalMalaria Journal
Volume7
DOIs
Publication statusPublished - Nov 2008

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