Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia

Brigid Orr; Griet Vanpoucke; O Cathal Grace; Lee Smith; Richard A Anderson; Antony C P Riddick; Omar E Franco; Simon W Hayward; Axel A Thomson

doi:10.1002/pros.21244

Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia

Brigid Orr, Griet Vanpoucke, O Cathal Grace, Lee Smith, Richard A Anderson, Antony C P Riddick, Omar E Franco, Simon W Hayward, Axel A Thomson

Research output: Contribution to journal › Article › peer-review

Abstract

Androgens and paracrine signaling from mesenchyme/stroma regulate development and disease of the prostate, and gene profiling studies of inductive prostate mesenchyme have identified candidate molecules such as pleiotrophin (Ptn).

Original language	English
Pages (from-to)	305-17
Number of pages	13
Journal	Prostate
Volume	71
Issue number	3
DOIs	https://doi.org/10.1002/pros.21244
Publication status	Published - 2011

Access to Document

10.1002/pros.21244

Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia
Available under Open Access
Final published version, 526 KB

http://onlinelibrary.wiley.com/doi/10.1002/pros.21244/abstract

Cite this

Orr, B., Vanpoucke, G., Grace, O. C., Smith, L., Anderson, R. A., Riddick, A. C. P., Franco, O. E., Hayward, S. W., & Thomson, A. A. (2011). Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia. Prostate, 71(3), 305-17. https://doi.org/10.1002/pros.21244

@article{fe55df14a78f44a8afaa5a337593c252,

title = "Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia",

abstract = "Androgens and paracrine signaling from mesenchyme/stroma regulate development and disease of the prostate, and gene profiling studies of inductive prostate mesenchyme have identified candidate molecules such as pleiotrophin (Ptn).",

author = "Brigid Orr and Griet Vanpoucke and Grace, {O Cathal} and Lee Smith and Anderson, {Richard A} and Riddick, {Antony C P} and Franco, {Omar E} and Hayward, {Simon W} and Thomson, {Axel A}",

note = "Copyright {\textcopyright} 2010 Wiley-Liss, Inc.",

year = "2011",

doi = "10.1002/pros.21244",

language = "English",

volume = "71",

pages = "305--17",

journal = "Prostate",

issn = "0270-4137",

publisher = "Wiley",

number = "3",

}

Orr, B, Vanpoucke, G, Grace, OC, Smith, L, Anderson, RA, Riddick, ACP, Franco, OE, Hayward, SW & Thomson, AA 2011, 'Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia', Prostate, vol. 71, no. 3, pp. 305-17. https://doi.org/10.1002/pros.21244

TY - JOUR

T1 - Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia

AU - Orr, Brigid

AU - Vanpoucke, Griet

AU - Grace, O Cathal

AU - Smith, Lee

AU - Anderson, Richard A

AU - Riddick, Antony C P

AU - Franco, Omar E

AU - Hayward, Simon W

AU - Thomson, Axel A

PY - 2011

Y1 - 2011

N2 - Androgens and paracrine signaling from mesenchyme/stroma regulate development and disease of the prostate, and gene profiling studies of inductive prostate mesenchyme have identified candidate molecules such as pleiotrophin (Ptn).

AB - Androgens and paracrine signaling from mesenchyme/stroma regulate development and disease of the prostate, and gene profiling studies of inductive prostate mesenchyme have identified candidate molecules such as pleiotrophin (Ptn).

U2 - 10.1002/pros.21244

DO - 10.1002/pros.21244

M3 - Article

C2 - 20812209

VL - 71

SP - 305

EP - 317

JO - Prostate

JF - Prostate

SN - 0270-4137

IS - 3

ER -

Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia

Abstract

Access to Document

Fingerprint

Cite this