Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis

T J Nuttall; P A Knight; S M McAleese; J R Lamb; P B Hill

Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis

T J Nuttall, P A Knight, S M McAleese, J R Lamb, P B Hill

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Atopic dermatitis is a common inflammatory skin disease of humans and dogs. Human atopic dermatitis is associated with Th2-type responses, although Th1 cytokines can be identified in chronic lesions. In contrast, tolerance to environmental allergens in healthy individuals is mediated by regulatory T cells.

Original language	English
Pages (from-to)	789-95
Number of pages	7
Journal	Clinical & Experimental Allergy
Volume	32
Issue number	5
Publication status	Published - May 2002

Keywords / Materials (for Non-textual outputs)

Animals
Cytokines
Dermatitis, Atopic
Dermatitis, Contact
Dog Diseases
Dogs
Humans
Immunosuppressive Agents
Interleukin-10
RNA, Messenger
Th1 Cells
Th2 Cells
Transcription, Genetic
Transforming Growth Factor beta

Cite this

@article{7293b553a43f4e889600e1ae1dc20a28,

title = "Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis",

abstract = "Atopic dermatitis is a common inflammatory skin disease of humans and dogs. Human atopic dermatitis is associated with Th2-type responses, although Th1 cytokines can be identified in chronic lesions. In contrast, tolerance to environmental allergens in healthy individuals is mediated by regulatory T cells.",

keywords = "Animals, Cytokines, Dermatitis, Atopic, Dermatitis, Contact, Dog Diseases, Dogs, Humans, Immunosuppressive Agents, Interleukin-10, RNA, Messenger, Th1 Cells, Th2 Cells, Transcription, Genetic, Transforming Growth Factor beta",

author = "Nuttall, {T J} and Knight, {P A} and McAleese, {S M} and Lamb, {J R} and Hill, {P B}",

year = "2002",

month = may,

language = "English",

volume = "32",

pages = "789--95",

journal = "Clinical & Experimental Allergy",

issn = "0954-7894",

publisher = "Wiley",

number = "5",

}

TY - JOUR

T1 - Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis

AU - Nuttall, T J

AU - Knight, P A

AU - McAleese, S M

AU - Lamb, J R

AU - Hill, P B

PY - 2002/5

Y1 - 2002/5

N2 - Atopic dermatitis is a common inflammatory skin disease of humans and dogs. Human atopic dermatitis is associated with Th2-type responses, although Th1 cytokines can be identified in chronic lesions. In contrast, tolerance to environmental allergens in healthy individuals is mediated by regulatory T cells.

AB - Atopic dermatitis is a common inflammatory skin disease of humans and dogs. Human atopic dermatitis is associated with Th2-type responses, although Th1 cytokines can be identified in chronic lesions. In contrast, tolerance to environmental allergens in healthy individuals is mediated by regulatory T cells.

KW - Animals

KW - Cytokines

KW - Dermatitis, Atopic

KW - Dermatitis, Contact

KW - Dog Diseases

KW - Dogs

KW - Humans

KW - Immunosuppressive Agents

KW - Interleukin-10

KW - RNA, Messenger

KW - Th1 Cells

KW - Th2 Cells

KW - Transcription, Genetic

KW - Transforming Growth Factor beta

M3 - Article

C2 - 11994107

SN - 0954-7894

VL - 32

SP - 789

EP - 795

JO - Clinical & Experimental Allergy

JF - Clinical & Experimental Allergy

IS - 5

ER -

Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

Fingerprint

Cite this