Extracellular Vesicles for the Diagnosis of Cancers

Yuxiang Xue, Xue Feng, Xianfeng Fan, Guangyu Zhu, James McLaughlan, Wenjun Zhang*, Michael Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Extracellular vesicles (EVs) are ultra-small structures secreted by various types of cells and carry biomarkers such as DNA, RNA, and the protein of the cells that secreted them. Cancer-cell-derived EVs can be detected at the very early stage of cancers, and hence the use of EVs for cancer diagnosis has aroused significant interest. This review summarizes the representative strategies of using EVs as biomarkers to detect different types of cancers, evaluates their advantages and challenges, and discusses their development prospects for cancer early diagnosis.
Original languageEnglish
Article number2100096
Number of pages30
JournalSmall Structures
Issue number1
Early online date7 Dec 2021
Publication statusPublished - 13 Jan 2022


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