Extracellular Vesicles for the Diagnosis of Cancers

Yuxiang Xue; Xue Feng; Xianfeng Fan; Guangyu Zhu; James McLaughlan; Wenjun Zhang; Michael Chen

doi:10.1002/sstr.202100096

Extracellular Vesicles for the Diagnosis of Cancers

Yuxiang Xue, Xue Feng, Xianfeng Fan, Guangyu Zhu, James McLaughlan, Wenjun Zhang^*, Michael Chen^*

^*Corresponding author for this work

School of Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Extracellular vesicles (EVs) are ultra-small structures secreted by various types of cells and carry biomarkers such as DNA, RNA, and the protein of the cells that secreted them. Cancer-cell-derived EVs can be detected at the very early stage of cancers, and hence the use of EVs for cancer diagnosis has aroused significant interest. This review summarizes the representative strategies of using EVs as biomarkers to detect different types of cancers, evaluates their advantages and challenges, and discusses their development prospects for cancer early diagnosis.

Original language	English
Article number	2100096
Number of pages	30
Journal	Small Structures
Volume	3
Issue number	1
Early online date	7 Dec 2021
DOIs	https://doi.org/10.1002/sstr.202100096
Publication status	Published - 13 Jan 2022

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title = "Extracellular Vesicles for the Diagnosis of Cancers",

abstract = "Extracellular vesicles (EVs) are ultra-small structures secreted by various types of cells and carry biomarkers such as DNA, RNA, and the protein of the cells that secreted them. Cancer-cell-derived EVs can be detected at the very early stage of cancers, and hence the use of EVs for cancer diagnosis has aroused significant interest. This review summarizes the representative strategies of using EVs as biomarkers to detect different types of cancers, evaluates their advantages and challenges, and discusses their development prospects for cancer early diagnosis.",

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AU - Fan, Xianfeng

AU - Zhu, Guangyu

AU - McLaughlan, James

AU - Zhang, Wenjun

AU - Chen, Michael

PY - 2022/1/13

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AB - Extracellular vesicles (EVs) are ultra-small structures secreted by various types of cells and carry biomarkers such as DNA, RNA, and the protein of the cells that secreted them. Cancer-cell-derived EVs can be detected at the very early stage of cancers, and hence the use of EVs for cancer diagnosis has aroused significant interest. This review summarizes the representative strategies of using EVs as biomarkers to detect different types of cancers, evaluates their advantages and challenges, and discusses their development prospects for cancer early diagnosis.

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Extracellular Vesicles for the Diagnosis of Cancers

Abstract

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