Abstract
We have investigated the occurrence of attenuated extracolonic manifestations (AEMs) of familial adenomatous polyposis (FAP) in patients with non-polyposis colorectal cancer. In a prospective case-control study, we observed that significantly more colorectal cancer patients exhibited AEM than did age and sex-matched controls (19.5% vs 7.5%, P
Original language | English |
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Pages (from-to) | 1789-95 |
Number of pages | 7 |
Journal | British Journal of Cancer |
Volume | 74 |
Issue number | 11 |
Publication status | Published - Dec 1996 |
Keywords
- Adenomatous Polyposis Coli
- Adult
- Aged
- Aged, 80 and over
- Case-Control Studies
- Colorectal Neoplasms
- DNA Mutational Analysis
- DNA Replication
- DNA, Neoplasm
- Female
- Genes, APC
- Humans
- Hypertrophy
- Male
- Middle Aged
- Neoplasm Staging
- Phenotype
- Pigment Epithelium of Eye
- Prospective Studies