Family load impacts orbitofrontal volume in first-episode schizophrenia

Berend Malchow, Alkomiet Hasan, Kristina Meyer, Thomas Schneider-Axmann, Katrin E Radenbach, Oliver Gruber, Wolfgang Reith, Andrew M McIntosh, Andrea Schmitt, Peter Falkai, Thomas Wobrock

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

In schizophrenia, reduced orbitofrontal cortex (OFC) volume is inconsistently reported. To investigate the impact of genetic load on OFC volume, manual MRI-tracing in 23 first-episode schizophrenia patients (FE-SZ) and 23 controls was performed. FE-SZ with genetic load showed a decrease in OFC volume compared to FE-SZ without load and controls.

Original languageEnglish
Pages (from-to)130-3
Number of pages4
JournalPsychiatry Research
Issue number1
Publication statusPublished - 30 Apr 2015


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