Family load impacts orbitofrontal volume in first-episode schizophrenia

Berend Malchow; Alkomiet Hasan; Kristina Meyer; Thomas Schneider-Axmann; Katrin E Radenbach; Oliver Gruber; Wolfgang Reith; Andrew M McIntosh; Andrea Schmitt; Peter Falkai; Thomas Wobrock

doi:10.1016/j.pscychresns.2015.02.006

Family load impacts orbitofrontal volume in first-episode schizophrenia

Berend Malchow, Alkomiet Hasan, Kristina Meyer, Thomas Schneider-Axmann, Katrin E Radenbach, Oliver Gruber, Wolfgang Reith, Andrew M McIntosh, Andrea Schmitt, Peter Falkai, Thomas Wobrock

Research output: Contribution to journal › Article › peer-review

Abstract

In schizophrenia, reduced orbitofrontal cortex (OFC) volume is inconsistently reported. To investigate the impact of genetic load on OFC volume, manual MRI-tracing in 23 first-episode schizophrenia patients (FE-SZ) and 23 controls was performed. FE-SZ with genetic load showed a decrease in OFC volume compared to FE-SZ without load and controls.

Original language	English
Pages (from-to)	130-3
Number of pages	4
Journal	Psychiatry Research
Volume	232
Issue number	1
DOIs	https://doi.org/10.1016/j.pscychresns.2015.02.006
Publication status	Published - 30 Apr 2015

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10.1016/j.pscychresns.2015.02.006

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title = "Family load impacts orbitofrontal volume in first-episode schizophrenia",

abstract = "In schizophrenia, reduced orbitofrontal cortex (OFC) volume is inconsistently reported. To investigate the impact of genetic load on OFC volume, manual MRI-tracing in 23 first-episode schizophrenia patients (FE-SZ) and 23 controls was performed. FE-SZ with genetic load showed a decrease in OFC volume compared to FE-SZ without load and controls.",

author = "Berend Malchow and Alkomiet Hasan and Kristina Meyer and Thomas Schneider-Axmann and Radenbach, \{Katrin E\} and Oliver Gruber and Wolfgang Reith and McIntosh, \{Andrew M\} and Andrea Schmitt and Peter Falkai and Thomas Wobrock",

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T1 - Family load impacts orbitofrontal volume in first-episode schizophrenia

AU - Malchow, Berend

AU - Hasan, Alkomiet

AU - Meyer, Kristina

AU - Schneider-Axmann, Thomas

AU - Radenbach, Katrin E

AU - Gruber, Oliver

AU - Reith, Wolfgang

AU - McIntosh, Andrew M

AU - Schmitt, Andrea

AU - Falkai, Peter

AU - Wobrock, Thomas

PY - 2015/4/30

Y1 - 2015/4/30

N2 - In schizophrenia, reduced orbitofrontal cortex (OFC) volume is inconsistently reported. To investigate the impact of genetic load on OFC volume, manual MRI-tracing in 23 first-episode schizophrenia patients (FE-SZ) and 23 controls was performed. FE-SZ with genetic load showed a decrease in OFC volume compared to FE-SZ without load and controls.

AB - In schizophrenia, reduced orbitofrontal cortex (OFC) volume is inconsistently reported. To investigate the impact of genetic load on OFC volume, manual MRI-tracing in 23 first-episode schizophrenia patients (FE-SZ) and 23 controls was performed. FE-SZ with genetic load showed a decrease in OFC volume compared to FE-SZ without load and controls.

U2 - 10.1016/j.pscychresns.2015.02.006

DO - 10.1016/j.pscychresns.2015.02.006

M3 - Article

C2 - 25800218

SN - 0165-1781

VL - 232

SP - 130

EP - 133

JO - Psychiatry Research

JF - Psychiatry Research

IS - 1

ER -

Family load impacts orbitofrontal volume in first-episode schizophrenia

Abstract

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