Fast and Selective Hydroaminomethylation Using Xanthene-Based Amino-Functionalized Ligands

Bart Hamers, Etienne Kosciusko-Morizet, Christian Muller, Dieter Vogt

Research output: Contribution to journalArticlepeer-review

Abstract

Hydroaminomethylation of 1-octene and piperidine has been carried out using a pyrrole-substituted phosphine ligand (see Scheme; L), giving extremely high activities (TOF≈6200 h−1) and selectivities (linear/branched ratios>200). Acidic alcohols in the solvent mixture lead to higher activities but lower selectivities, whereas less acidic alcohols give extraordinarily good selectivities.
Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalChemCatChe
Volume1
Issue number1
DOIs
Publication statusPublished - Aug 2009

Keywords

  • amines
  • chemoselectivity
  • homogeneous catalysis
  • P ligands
  • regioselectivity

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