Feeding management before gastrointestinal studies in pigs

Rachael Gregson, Stephen Greenhalgh, Benjamin Cox, Sandy Cochrane, Eddie Clutton

Research output: Contribution to journalComment/debatepeer-review


Pigs are used to model humans in gastrointestinal studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) required a clean, motile small intestine. Recommendations for human gastrointestinal tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives while high carbohydrate drinks are recommended before colorectal surgery. Reports of gastrointestinal preparation of pigs exist but lack technical details i.e. administration, efficacy, side-effects.
This report details feeding a high-energy liquid diet to eleven female pigs undergoing surgery and USCE which was readily accepted, easily administered, produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.

Original languageEnglish
JournalLaboratory Animals
Early online date12 Oct 2020
Publication statusE-pub ahead of print - 12 Oct 2020


  • Pigs
  • Anaesthesia
  • Food withdrawal
  • Refinement
  • Gastrointestinal Tract
  • Capsule Endoscopy
  • Colorectal Surgery


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