Fine mapping of a human chromosome 6 ferritin heavy chain pseudogene: relevance to haemochromatosis

K M Summers; K S Tam; P B Bartley; J Drysdale; H Y Zoghbi; J W Halliday; L W Powell

Fine mapping of a human chromosome 6 ferritin heavy chain pseudogene: relevance to haemochromatosis

K M Summers, K S Tam, P B Bartley, J Drysdale, H Y Zoghbi, J W Halliday, L W Powell

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

We have used a somatic cell hybrid regional mapping panel for the short arm of chromosome 6, linkage analysis and a population study to map in detail a previously described ferritin heavy chain pseudogene sequence on chromosome 6. Our results show that this sequence maps to the short arm of chromosome 6 centromeric to the glyoxylase locus. The ferritin pseudogene locus is thus distant from the locus for the iron storage disease haemochromatosis, confirming previous evidence that this sequence is not a candidate for the haemochromatosis gene.

Original language	English
Pages (from-to)	175-8
Number of pages	4
Journal	Human Genetics
Volume	88
Issue number	2
Publication status	Published - 1991

Cite this

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title = "Fine mapping of a human chromosome 6 ferritin heavy chain pseudogene: relevance to haemochromatosis",

abstract = "We have used a somatic cell hybrid regional mapping panel for the short arm of chromosome 6, linkage analysis and a population study to map in detail a previously described ferritin heavy chain pseudogene sequence on chromosome 6. Our results show that this sequence maps to the short arm of chromosome 6 centromeric to the glyoxylase locus. The ferritin pseudogene locus is thus distant from the locus for the iron storage disease haemochromatosis, confirming previous evidence that this sequence is not a candidate for the haemochromatosis gene.",

author = "Summers, {K M} and Tam, {K S} and Bartley, {P B} and J Drysdale and Zoghbi, {H Y} and Halliday, {J W} and Powell, {L W}",

year = "1991",

language = "English",

volume = "88",

pages = "175--8",

journal = "Human Genetics",

issn = "0340-6717",

publisher = "Springer Verlag",

number = "2",

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TY - JOUR

T1 - Fine mapping of a human chromosome 6 ferritin heavy chain pseudogene

T2 - relevance to haemochromatosis

AU - Summers, K M

AU - Tam, K S

AU - Bartley, P B

AU - Drysdale, J

AU - Zoghbi, H Y

AU - Halliday, J W

AU - Powell, L W

PY - 1991

Y1 - 1991

N2 - We have used a somatic cell hybrid regional mapping panel for the short arm of chromosome 6, linkage analysis and a population study to map in detail a previously described ferritin heavy chain pseudogene sequence on chromosome 6. Our results show that this sequence maps to the short arm of chromosome 6 centromeric to the glyoxylase locus. The ferritin pseudogene locus is thus distant from the locus for the iron storage disease haemochromatosis, confirming previous evidence that this sequence is not a candidate for the haemochromatosis gene.

AB - We have used a somatic cell hybrid regional mapping panel for the short arm of chromosome 6, linkage analysis and a population study to map in detail a previously described ferritin heavy chain pseudogene sequence on chromosome 6. Our results show that this sequence maps to the short arm of chromosome 6 centromeric to the glyoxylase locus. The ferritin pseudogene locus is thus distant from the locus for the iron storage disease haemochromatosis, confirming previous evidence that this sequence is not a candidate for the haemochromatosis gene.

M3 - Article

C2 - 1757092

VL - 88

SP - 175

EP - 178

JO - Human Genetics

JF - Human Genetics

SN - 0340-6717

IS - 2

ER -

Fine mapping of a human chromosome 6 ferritin heavy chain pseudogene: relevance to haemochromatosis

Abstract

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