TY - JOUR
T1 - Fluorescence correlation spectroscopy
T2 - Lead discovery by miniaturized HTS
AU - Auer, M.
AU - Moore, K.J.
AU - Meyer-Almes, F.J.
AU - Guenther, R.
AU - Pope, A.J.
AU - Stoeckli, K.A.
N1 - Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.
PY - 1999/1/1
Y1 - 1999/1/1
N2 - Miniaturized high-throughput screening offers great promise for increasing the productivity of the pharmaceutical drug discovery process. By monitoring interactions of single molecules in femtoliter volumes, fluorescence correlation spectroscopy (FCS) offers the highest potential as the detection technique in the nanoscale. The authors () summarize the current status of practical experiences with FCS assays for HTS and explore the scope for further developments. Copyright (C) 1998 Elsevier Science Ltd.
AB - Miniaturized high-throughput screening offers great promise for increasing the productivity of the pharmaceutical drug discovery process. By monitoring interactions of single molecules in femtoliter volumes, fluorescence correlation spectroscopy (FCS) offers the highest potential as the detection technique in the nanoscale. The authors () summarize the current status of practical experiences with FCS assays for HTS and explore the scope for further developments. Copyright (C) 1998 Elsevier Science Ltd.
UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-0033053481&md5=2f59b886217da1bc1247691ef20d29a0
M3 - Article
AN - SCOPUS:0033053481
SN - 0192-0561
VL - 21
SP - 457
EP - 465
JO - International Journal of Immunopharmacology
JF - International Journal of Immunopharmacology
IS - 2
ER -