Fluorescence correlation spectroscopy: Lead discovery by miniaturized HTS

M. Auer; K.J. Moore; F.J. Meyer-Almes; R. Guenther; A.J. Pope; K.A. Stoeckli

Fluorescence correlation spectroscopy: Lead discovery by miniaturized HTS

M. Auer, K.J. Moore, F.J. Meyer-Almes, R. Guenther, A.J. Pope, K.A. Stoeckli

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Miniaturized high-throughput screening offers great promise for increasing the productivity of the pharmaceutical drug discovery process. By monitoring interactions of single molecules in femtoliter volumes, fluorescence correlation spectroscopy (FCS) offers the highest potential as the detection technique in the nanoscale. The authors () summarize the current status of practical experiences with FCS assays for HTS and explore the scope for further developments. Copyright (C) 1998 Elsevier Science Ltd.

Original language	English
Pages (from-to)	457-465
Number of pages	9
Journal	International Journal of Immunopharmacology
Volume	21
Issue number	2
Publication status	Published - 1 Jan 1999

Cite this

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Fluorescence correlation spectroscopy: Lead discovery by miniaturized HTS

Abstract

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