Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates

Leila Vali; Sarah E Davies; Lindsay L G Lai; Jayshree Dave; Sebastian G B Amyes

doi:10.1093/jac/dkm520

Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates

Leila Vali, Sarah E Davies, Lindsay L G Lai, Jayshree Dave, Sebastian G B Amyes

Research output: Contribution to journal › Article › peer-review

Abstract

To detect genes conferring resistance to biguanides, quaternary ammonium compounds, beta-lactams and fluoroquinolones in clinical methicillin-resistant Staphylococcus aureus (MRSA) and to demonstrate whether reduced susceptibility is spread clonally and if the presence of any of the detected genes links to a specific epidemic MRSA. Finally, to identify if exposure to chlorhexidine may cause reduced susceptibility to antibiotics and chlorhexidine.

Original language	English
Pages (from-to)	524-32
Number of pages	9
Journal	Journal of Antimicrobial Chemotherapy
Volume	61
Issue number	3
DOIs	https://doi.org/10.1093/jac/dkm520
Publication status	Published - Mar 2008

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10.1093/jac/dkm520

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title = "Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates",

abstract = "To detect genes conferring resistance to biguanides, quaternary ammonium compounds, beta-lactams and fluoroquinolones in clinical methicillin-resistant Staphylococcus aureus (MRSA) and to demonstrate whether reduced susceptibility is spread clonally and if the presence of any of the detected genes links to a specific epidemic MRSA. Finally, to identify if exposure to chlorhexidine may cause reduced susceptibility to antibiotics and chlorhexidine.",

author = "Leila Vali and Davies, {Sarah E} and Lai, {Lindsay L G} and Jayshree Dave and Amyes, {Sebastian G B}",

year = "2008",

month = mar,

doi = "10.1093/jac/dkm520",

language = "English",

volume = "61",

pages = "524--32",

journal = "Journal of Antimicrobial Chemotherapy",

issn = "0305-7453",

publisher = "Oxford University Press",

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Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates. / Vali, Leila; Davies, Sarah E; Lai, Lindsay L G; Dave, Jayshree; Amyes, Sebastian G B.

In: Journal of Antimicrobial Chemotherapy, Vol. 61, No. 3, 03.2008, p. 524-32.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates

AU - Vali, Leila

AU - Davies, Sarah E

AU - Lai, Lindsay L G

AU - Dave, Jayshree

AU - Amyes, Sebastian G B

PY - 2008/3

Y1 - 2008/3

N2 - To detect genes conferring resistance to biguanides, quaternary ammonium compounds, beta-lactams and fluoroquinolones in clinical methicillin-resistant Staphylococcus aureus (MRSA) and to demonstrate whether reduced susceptibility is spread clonally and if the presence of any of the detected genes links to a specific epidemic MRSA. Finally, to identify if exposure to chlorhexidine may cause reduced susceptibility to antibiotics and chlorhexidine.

AB - To detect genes conferring resistance to biguanides, quaternary ammonium compounds, beta-lactams and fluoroquinolones in clinical methicillin-resistant Staphylococcus aureus (MRSA) and to demonstrate whether reduced susceptibility is spread clonally and if the presence of any of the detected genes links to a specific epidemic MRSA. Finally, to identify if exposure to chlorhexidine may cause reduced susceptibility to antibiotics and chlorhexidine.

UR - http://www.scopus.com/inward/record.url?scp=40049106339&partnerID=8YFLogxK

U2 - 10.1093/jac/dkm520

DO - 10.1093/jac/dkm520

M3 - Article

C2 - 18227090

VL - 61

SP - 524

EP - 532

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

SN - 0305-7453

IS - 3

ER -

Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates

Abstract

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