Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolates

Leila Vali, Sarah E Davies, Lindsay L G Lai, Jayshree Dave, Sebastian G B Amyes

Research output: Contribution to journalArticlepeer-review

Abstract

To detect genes conferring resistance to biguanides, quaternary ammonium compounds, beta-lactams and fluoroquinolones in clinical methicillin-resistant Staphylococcus aureus (MRSA) and to demonstrate whether reduced susceptibility is spread clonally and if the presence of any of the detected genes links to a specific epidemic MRSA. Finally, to identify if exposure to chlorhexidine may cause reduced susceptibility to antibiotics and chlorhexidine.
Original languageEnglish
Pages (from-to)524-32
Number of pages9
JournalJournal of Antimicrobial Chemotherapy
Volume61
Issue number3
DOIs
Publication statusPublished - Mar 2008

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