Fructosamine concentration and resistance to natural, predominantly Teladorsagia circumcincta infection

MJ Stear*, PD Eckersall, PA Graham, QA McKellar, S Mitchell, SC Bishop

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Fructosamine con cent rations reflect protein status and because infection with Teladorsagia circumcineta can induce a relative protein deficiency, we examined the usefulness of fructosamine concentrations as markers of the intensity of infection in naturally infected lambs. Fructosamine concentration was a heritable trait and variation in fructosamine concentrations was associated with differences in body weight, and a variety of parasitological variables; animals with increased fructosamine concentrations grew more quickly, had increased faecal egg counts in one of the three study years, had decreased pepsinogen concentrations and decreased IgA activity against 4th-stage larvae of T. circumcineta. Fructosamine concentrations were also associated with variation in the subsequent acquisition of nematodes and in the length of adult female T circumcineta; lambs with increased fructosamine concentrations had fewer nematodes but the mean length of adult female T. circumcineta was longer. Therefore fructosamine concentrations are potentially useful indicators of the severity of nematode infection and may predict magnitude of subsequent infection.

Original languageEnglish
Pages (from-to)211-218
Number of pages8
JournalParasitology
Volume123
Publication statusPublished - Aug 2001

Keywords

  • sheep
  • Nematoda
  • Teladorsagia circumcincta
  • fructosamine
  • marker
  • indicator trait
  • OSTERTAGIA-CIRCUMCINCTA
  • GASTROINTESTINAL NEMATODES
  • ANTHELMINTIC TREATMENT
  • PARASITE INTERACTION
  • YOUNG LAMBS
  • SHEEP
  • PLASMA
  • STRATEGIES
  • NUTRITION
  • NUMBER

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