Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities

Jiangkun Dai, Na Li, Junru Wang, Uwe Schneider

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

In this review, more than 60 natural canthin-6-one alkaloids and their structures are considered. The biosynthesis, efficient and classic synthetic approaches, and biological activities of canthin-6-one alkaloids, from 1952 to 2015, are discussed. From an analysis of their structural properties and an investigation of the literature, possible future trends for canthin-6-one alkaloids are proposed. The information reported will be helpful in future research on canthin-6-one alkaloids.

Original languageEnglish
Article number493
Number of pages13
JournalMolecules
Volume21
Issue number4
DOIs
Publication statusPublished - 15 Apr 2016

Keywords

  • canthin-6-one
  • biosynthesis
  • chemistry
  • biological activities
  • BETA-CARBOLINE ALKALOIDS
  • CHILOPERONE VAR. ANGUSTIFOLIUM
  • CATALYZED AMIDATION REACTION
  • NITRIC-OXIDE PRODUCTION
  • EURYCOMA-LONGIFOLIA
  • ZANTHOXYLUM-CHILOPERONE
  • AILANTHUS-ALTISSIMA
  • 5,5-DISUBSTITUTED 4,5-DIHYDRO-6H-CANTHIN-6-ONES
  • ANTIPROLIFERATIVE ACTIVITY
  • ANTIMALARIAL CONSTITUENTS

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