Future perspectives on swine viral vaccines: where are we headed?

Tanja Opriessnig, Ashley A. Mattei, Anbu K Karuppannan, Patrick G Halbur

Research output: Contribution to journalReview articlepeer-review

Abstract

Deliberate infection of humans with smallpox, also known as variolation, was a common practice in Asia and dates back to the 15th century. The world’s first human vaccination was administered in 1796 by Edward Jenner, a British physician. One of the first pig vaccines, which targeted the bacterium Erysipelothrix rhusiopathiae, was introduced in 1883 in France by Louis Pasteur. Since then vaccination has become an essential part of pig production, and viral vaccines in particular are essential tools for pig producers and veterinarians to manage pig herd health. Traditionally, viral vaccines for pigs are either based on attenuated-live virus strains or inactivated viral antigens. With the advent of genomic sequencing and molecular engineering, novel vaccine strategies and tools, including subunit and nucleic acid vaccines, became available and are being increasingly used in pigs. This review aims to summarize recent trends and technologies available for the production and use of vaccines targeting pig viruses.
Original languageEnglish
JournalPorcine Health Management
DOIs
Publication statusPublished - 4 Jan 2021

Keywords

  • Vaccines
  • Review
  • Viruses, pigs

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