Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis

Karin Allenspach; Andreas Handel; Stanley Marks; Peter Kook; Kenny Simpson; Joseph Bartges; Kenjiro Fukushima; Aarti Kathrani; Silke Salavati; Julien Dandrieux; Caroline Mansfield; Alison Manchester; Craig Webb; Valerie Freiche; W Zane Billings; Jonathan P Mochel

doi:10.1111/jvim.17025

Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis

Karin Allenspach, Andreas Handel, Stanley Marks, Peter Kook, Kenny Simpson, Joseph Bartges, Kenjiro Fukushima, Aarti Kathrani, Silke Salavati, Julien Dandrieux, Caroline Mansfield, Alison Manchester, Craig Webb, Valerie Freiche, W Zane Billings, Jonathan P Mochel

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Letter › peer-review

Abstract / Description of output

We read with interest the article by Steiner et al,1 that claims that administration of fuzapladib is safe and effective in reducing 2 clinical scores in dogs with acute pancreatitis (AP). We commend Steiner et al for their efforts in addressing a critical need in veterinary medicine. This letter, however, raises significant concerns regarding the methodology and interpretation of the study results.

Original language	English
Pages (from-to)	1282-1284
Number of pages	3
Journal	Journal of Veterinary Internal Medicine
Volume	38
Issue number	3
Early online date	5 Mar 2024
DOIs	https://doi.org/10.1111/jvim.17025
Publication status	E-pub ahead of print - 5 Mar 2024

Keywords / Materials (for Non-textual outputs)

Animals
Dog Diseases/diagnosis
Dogs
Pancreatitis/veterinary
Randomized Controlled Trials as Topic

Access to Document

10.1111/jvim.17025

Veterinary Internal Medicne - 2024 - Allenspach - Letter regarding Fuzapladib in a randomized controlled multicenter (1)Final published version, 170 KBLicence: Creative Commons: Attribution (CC-BY)

Cite this

Allenspach, K., Handel, A., Marks, S., Kook, P., Simpson, K., Bartges, J., Fukushima, K., Kathrani, A., Salavati, S., Dandrieux, J., Mansfield, C., Manchester, A., Webb, C., Freiche, V., Billings, W. Z., & Mochel, J. P. (2024). Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis. Journal of Veterinary Internal Medicine, 38(3), 1282-1284. Advance online publication. https://doi.org/10.1111/jvim.17025

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title = "Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis",

abstract = "We read with interest the article by Steiner et al,1 that claims that administration of fuzapladib is safe and effective in reducing 2 clinical scores in dogs with acute pancreatitis (AP). We commend Steiner et al for their efforts in addressing a critical need in veterinary medicine. This letter, however, raises significant concerns regarding the methodology and interpretation of the study results.",

keywords = "Animals, Dog Diseases/diagnosis, Dogs, Pancreatitis/veterinary, Randomized Controlled Trials as Topic",

author = "Karin Allenspach and Andreas Handel and Stanley Marks and Peter Kook and Kenny Simpson and Joseph Bartges and Kenjiro Fukushima and Aarti Kathrani and Silke Salavati and Julien Dandrieux and Caroline Mansfield and Alison Manchester and Craig Webb and Valerie Freiche and Billings, {W Zane} and Mochel, {Jonathan P}",

year = "2024",

month = mar,

day = "5",

doi = "10.1111/jvim.17025",

language = "English",

volume = "38",

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}

Allenspach, K, Handel, A, Marks, S, Kook, P, Simpson, K, Bartges, J, Fukushima, K, Kathrani, A, Salavati, S , Dandrieux, J, Mansfield, C, Manchester, A, Webb, C, Freiche, V, Billings, WZ & Mochel, JP 2024, 'Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis', Journal of Veterinary Internal Medicine, vol. 38, no. 3, pp. 1282-1284. https://doi.org/10.1111/jvim.17025

TY - JOUR

T1 - Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis

AU - Allenspach, Karin

AU - Handel, Andreas

AU - Marks, Stanley

AU - Kook, Peter

AU - Simpson, Kenny

AU - Bartges, Joseph

AU - Fukushima, Kenjiro

AU - Kathrani, Aarti

AU - Salavati, Silke

AU - Dandrieux, Julien

AU - Mansfield, Caroline

AU - Manchester, Alison

AU - Webb, Craig

AU - Freiche, Valerie

AU - Billings, W Zane

AU - Mochel, Jonathan P

PY - 2024/3/5

Y1 - 2024/3/5

N2 - We read with interest the article by Steiner et al,1 that claims that administration of fuzapladib is safe and effective in reducing 2 clinical scores in dogs with acute pancreatitis (AP). We commend Steiner et al for their efforts in addressing a critical need in veterinary medicine. This letter, however, raises significant concerns regarding the methodology and interpretation of the study results.

AB - We read with interest the article by Steiner et al,1 that claims that administration of fuzapladib is safe and effective in reducing 2 clinical scores in dogs with acute pancreatitis (AP). We commend Steiner et al for their efforts in addressing a critical need in veterinary medicine. This letter, however, raises significant concerns regarding the methodology and interpretation of the study results.

KW - Animals

KW - Dog Diseases/diagnosis

KW - Dogs

KW - Pancreatitis/veterinary

KW - Randomized Controlled Trials as Topic

U2 - 10.1111/jvim.17025

DO - 10.1111/jvim.17025

M3 - Letter

C2 - 38441383

SN - 0891-6640

VL - 38

SP - 1282

EP - 1284

JO - Journal of Veterinary Internal Medicine

JF - Journal of Veterinary Internal Medicine

IS - 3

ER -

Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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