GALLSTONES IN DIABETES-MELLITUS - PREVALENCE AND RISK-FACTORS

PC HAYES*, A PATRICK, JE ROULSTON, JT MURCHISON, P ALLAN, JN PLEVRIS, BE CLARKE, IAD BOUCHIER, John Plevris

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Objective: To identify the prevalence and risk factors for gallstone disease in both insulin-dependent and non-insulin-dependent diabetes mellitus compared with controls.

Design: A prospective blinded, ultrasonographic study of a diabetic population with age- and sex-matched controls.

Setting: Hospital-based.

Patients: Randomly selected patients attending hospital out-patient clinics; controls recruited consecutively, within the constraints of matching for age and sex.

Intervention: None.

Main outcome measures: Prevalence of gallstone disease in patient and control population. Risk factors for gallstone disease in diabetic patients including anthropomorphic and biochemical data.

Results: The prevalence of gallstone disease was only increased in diabetic patients compared with controls in the seventh decade (41% versus 17%). Independent risk factors were female gender, age, body mass index and plasma apolipoprotein A levels.

Conclusions: The risk of gallstone disease in diabetes mellitus is only increased in the elderly. The type of diabetes, quality of control and duration were not independent risk factors.

Original languageEnglish
Pages (from-to)55-59
Number of pages5
JournalEuropean Journal of Gastroenterology & Hepatology
Volume4
Issue number1
Publication statusPublished - Jan 1992

Keywords / Materials (for Non-textual outputs)

  • GALLSTONES
  • DIABETES-MELLITUS
  • APOLIPOPROTEIN-A
  • ULTRASOUND

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