Gene copy number variation throughout the Plasmodium falciparum genome

Ian H Cheeseman; Natalia Gomez-Escobar; Celine K Carret; Alasdair Ivens; Lindsay B Stewart; Kevin K A Tetteh; David J Conway

doi:10.1186/1471-2164-10-353

Gene copy number variation throughout the Plasmodium falciparum genome

Ian H Cheeseman, Natalia Gomez-Escobar, Celine K Carret, Alasdair Ivens, Lindsay B Stewart, Kevin K A Tetteh, David J Conway

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Gene copy number variation (CNV) is responsible for several important phenotypes of the malaria parasite Plasmodium falciparum, including drug resistance, loss of infected erythrocyte cytoadherence and alteration of receptor usage for erythrocyte invasion. Despite the known effects of CNV, little is known about its extent throughout the genome.

Original language	English
Article number	353
Journal	BMC Genomics
Volume	10
DOIs	https://doi.org/10.1186/1471-2164-10-353
Publication status	Published - 2009

Keywords / Materials (for Non-textual outputs)

Animals
Comparative Genomic Hybridization
Oligonucleotide Array Sequence Analysis
DNA, Protozoan
Plasmodium falciparum
Gene Dosage
Genome, Protozoan
Gene Deletion

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10.1186/1471-2164-10-353

Gene copy number variation throughout the Plasmodium falciparum genome
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Cite this

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title = "Gene copy number variation throughout the Plasmodium falciparum genome",

abstract = "Gene copy number variation (CNV) is responsible for several important phenotypes of the malaria parasite Plasmodium falciparum, including drug resistance, loss of infected erythrocyte cytoadherence and alteration of receptor usage for erythrocyte invasion. Despite the known effects of CNV, little is known about its extent throughout the genome.",

keywords = "Animals, Comparative Genomic Hybridization, Oligonucleotide Array Sequence Analysis, DNA, Protozoan, Plasmodium falciparum, Gene Dosage, Genome, Protozoan, Gene Deletion",

author = "Cheeseman, {Ian H} and Natalia Gomez-Escobar and Carret, {Celine K} and Alasdair Ivens and Stewart, {Lindsay B} and Tetteh, {Kevin K A} and Conway, {David J}",

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doi = "10.1186/1471-2164-10-353",

language = "English",

volume = "10",

journal = "BMC Genomics",

publisher = "BioMed Central",

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T1 - Gene copy number variation throughout the Plasmodium falciparum genome

AU - Cheeseman, Ian H

AU - Gomez-Escobar, Natalia

AU - Carret, Celine K

AU - Ivens, Alasdair

AU - Stewart, Lindsay B

AU - Tetteh, Kevin K A

AU - Conway, David J

PY - 2009

Y1 - 2009

N2 - Gene copy number variation (CNV) is responsible for several important phenotypes of the malaria parasite Plasmodium falciparum, including drug resistance, loss of infected erythrocyte cytoadherence and alteration of receptor usage for erythrocyte invasion. Despite the known effects of CNV, little is known about its extent throughout the genome.

AB - Gene copy number variation (CNV) is responsible for several important phenotypes of the malaria parasite Plasmodium falciparum, including drug resistance, loss of infected erythrocyte cytoadherence and alteration of receptor usage for erythrocyte invasion. Despite the known effects of CNV, little is known about its extent throughout the genome.

KW - Animals

KW - Comparative Genomic Hybridization

KW - Oligonucleotide Array Sequence Analysis

KW - DNA, Protozoan

KW - Plasmodium falciparum

KW - Gene Dosage

KW - Genome, Protozoan

KW - Gene Deletion

U2 - 10.1186/1471-2164-10-353

DO - 10.1186/1471-2164-10-353

M3 - Article

C2 - 19653891

VL - 10

JO - BMC Genomics

JF - BMC Genomics

M1 - 353

ER -

Gene copy number variation throughout the Plasmodium falciparum genome

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

Access to Document

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Cite this