Gene Regulatory Networks: Methods and Protocols

Guido Sanguinetti (Editor), Van Anh Huynh-Thu (Editor)

Research output: Book/ReportBook

Abstract

This volume explores recent techniques for the computational inference of gene regulatory networks (GRNs). The chapters in this book cover topics such as methods to infer GRNs from time-varying data; the extraction of causal information from biological data; GRN inference from multiple heterogeneous data sets; non-parametric and hybrid statistical methods; the joint inference of differential networks; and mechanistic models of gene regulation dynamics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, descriptions of recently developed methods for GRN inference, applications of these methods on real and/ or simulated biological data, and step-by-step tutorials on the usage of associated software tools.
Cutting-edge and thorough, Gene Regulatory Networks: Methods and Protocols is an essential tool for evaluating the current research needed to further address the common challenges faced by specialists in this field.
Original languageEnglish
PublisherHumana Press
Number of pages285
ISBN (Electronic)978-1-4939-8881-5
ISBN (Print)978-1-4939-8881-5
DOIs
Publication statusPublished - 2019

Publication series

NameMethods in Molecular Biology Series Volume
PublisherHumana Press
Volume1883
ISSN (Print)1064-3745

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  • Gene Regulatory Network Inference: An Introductory Survey

    Huynh-Thu, V. A. & Sanguinetti, G., 2019, Gene Regulatory Networks: Methods and Protocols. Sanguinetti, G. & Huynh-Thu, V. A. (eds.). New York, NY: Springer, p. 1-23 23 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Tree-Based Learning of Regulatory Network Topologies and Dynamics with Jump3

    Huynh-Thu, V. A. & Sanguinetti, G., 2019, Gene Regulatory Networks: Methods and Protocols. Sanguinetti, G. & Huynh-Thu, V. A. (eds.). New York, NY: Springer, p. 217-233 17 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

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