General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial

S C Lewis; C P Warlow; A R Bodenham; B Colam; P M Rothwell; D Torgerson; D Dellagrammaticas; M Horrocks; C Liapis; A P Banning; M Gough; M J Gough; GALA Trial Collaborative Group; Gordon Murray

doi:10.1016/S0140-6736(08)61699-2

General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial

S C Lewis, C P Warlow, A R Bodenham, B Colam, P M Rothwell, D Torgerson, D Dellagrammaticas, M Horrocks, C Liapis, A P Banning, M Gough, M J Gough, GALA Trial Collaborative Group, Gordon Murray (Member of Group Organisation)

Research output: Contribution to journal › Article › peer-review

Abstract

The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery under general anaesthesia with that under local anaesthesia because prediction and avoidance of perioperative strokes might be easier under local anaesthesia than under general anaesthesia.

Original language	English
Pages (from-to)	2132-2142
Number of pages	11
Journal	The Lancet
Volume	372
Issue number	9656
DOIs	https://doi.org/10.1016/S0140-6736(08)61699-2
Publication status	Published - Dec 2008

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10.1016/S0140-6736(08)61699-2

http://www.sciencedirect.com/science/article/pii/S0140673608616992

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Lewis, S. C., Warlow, C. P., Bodenham, A. R., Colam, B., Rothwell, P. M., Torgerson, D., Dellagrammaticas, D., Horrocks, M., Liapis, C., Banning, A. P., Gough, M., Gough, M. J., GALA Trial Collaborative Group, & Murray, G. (2008). General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial. The Lancet, 372(9656), 2132-2142. https://doi.org/10.1016/S0140-6736(08)61699-2

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abstract = "The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery under general anaesthesia with that under local anaesthesia because prediction and avoidance of perioperative strokes might be easier under local anaesthesia than under general anaesthesia.",

author = "Lewis, {S C} and Warlow, {C P} and Bodenham, {A R} and B Colam and Rothwell, {P M} and D Torgerson and D Dellagrammaticas and M Horrocks and C Liapis and Banning, {A P} and M Gough and Gough, {M J} and {GALA Trial Collaborative Group} and Gordon Murray",

year = "2008",

month = dec,

doi = "10.1016/S0140-6736(08)61699-2",

language = "English",

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Lewis, SC , Warlow, CP, Bodenham, AR, Colam, B, Rothwell, PM, Torgerson, D, Dellagrammaticas, D, Horrocks, M, Liapis, C, Banning, AP, Gough, M, Gough, MJ, GALA Trial Collaborative Group & Murray, G 2008, 'General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial', The Lancet, vol. 372, no. 9656, pp. 2132-2142. https://doi.org/10.1016/S0140-6736(08)61699-2

TY - JOUR

T1 - General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial

AU - Lewis, S C

AU - Warlow, C P

AU - Bodenham, A R

AU - Colam, B

AU - Rothwell, P M

AU - Torgerson, D

AU - Dellagrammaticas, D

AU - Horrocks, M

AU - Liapis, C

AU - Banning, A P

AU - Gough, M

AU - Gough, M J

AU - GALA Trial Collaborative Group

A2 - Murray, Gordon

PY - 2008/12

Y1 - 2008/12

N2 - The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery under general anaesthesia with that under local anaesthesia because prediction and avoidance of perioperative strokes might be easier under local anaesthesia than under general anaesthesia.

AB - The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery under general anaesthesia with that under local anaesthesia because prediction and avoidance of perioperative strokes might be easier under local anaesthesia than under general anaesthesia.

U2 - 10.1016/S0140-6736(08)61699-2

DO - 10.1016/S0140-6736(08)61699-2

M3 - Article

C2 - 19041130

SN - 0140-6736

VL - 372

SP - 2132

EP - 2142

JO - The Lancet

JF - The Lancet

IS - 9656

ER -

General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial

Abstract

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