Genes predict village of origin in rural Europe

Colm O'Dushlaine; Ruth McQuillan; Michael E. Weale; Daniel J. M. Crouch; Asa Johansson; Yurii Aulchenko; Christopher S. Franklin; Ozren Polasek; Christian Fuchsberger; Aiden Corvin; Andrew A. Hicks; Veronique Vitart; Caroline Hayward; Sarah H. Wild; Thomas Meitinger; Cornelia M. van Duijn; Ulf Gyllensten; Alan Wright; Harry Campbell; Peter P. Pramstaller; Igor Rudan; James F. Wilson

doi:10.1038/ejhg.2010.92

Genes predict village of origin in rural Europe

Colm O'Dushlaine, Ruth McQuillan, Michael E. Weale, Daniel J. M. Crouch, Asa Johansson, Yurii Aulchenko, Christopher S. Franklin, Ozren Polasek, Christian Fuchsberger, Aiden Corvin, Andrew A. Hicks, Veronique Vitart, Caroline Hayward, Sarah H. Wild, Thomas Meitinger, Cornelia M. van Duijn, Ulf Gyllensten, Alan Wright, Harry Campbell, Peter P. PramstallerIgor Rudan, James F. Wilson

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010

Original language	English
Pages (from-to)	1269-1270
Number of pages	2
Journal	European Journal of Human Genetics
Volume	18
Issue number	11
DOIs	https://doi.org/10.1038/ejhg.2010.92
Publication status	Published - Nov 2010

Keywords / Materials (for Non-textual outputs)

population structure
principal components
genome-wide genotyping

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10.1038/ejhg.2010.92

Genes predict village of origin in rural Europe
2010 Macmillan Publishers. Europepmc open access option
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http://www.nature.com/ejhg/journal/v18/n11/full/ejhg201092a.html

Cite this

O'Dushlaine, C., McQuillan, R., Weale, M. E., Crouch, D. J. M., Johansson, A., Aulchenko, Y., Franklin, C. S., Polasek, O., Fuchsberger, C., Corvin, A., Hicks, A. A., Vitart, V., Hayward, C., Wild, S. H., Meitinger, T., van Duijn, C. M., Gyllensten, U., Wright, A., Campbell, H., ... Wilson, J. F. (2010). Genes predict village of origin in rural Europe. European Journal of Human Genetics, 18(11), 1269-1270. https://doi.org/10.1038/ejhg.2010.92

@article{86fa4630472e4e929b2b6592cf2a81d0,

title = "Genes predict village of origin in rural Europe",

abstract = "The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010",

keywords = "population structure, principal components, genome-wide genotyping",

author = "Colm O'Dushlaine and Ruth McQuillan and Weale, {Michael E.} and Crouch, {Daniel J. M.} and Asa Johansson and Yurii Aulchenko and Franklin, {Christopher S.} and Ozren Polasek and Christian Fuchsberger and Aiden Corvin and Hicks, {Andrew A.} and Veronique Vitart and Caroline Hayward and Wild, {Sarah H.} and Thomas Meitinger and {van Duijn}, {Cornelia M.} and Ulf Gyllensten and Alan Wright and Harry Campbell and Pramstaller, {Peter P.} and Igor Rudan and Wilson, {James F.}",

year = "2010",

month = nov,

doi = "10.1038/ejhg.2010.92",

language = "English",

volume = "18",

pages = "1269--1270",

journal = "European Journal of Human Genetics",

issn = "1018-4813",

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O'Dushlaine, C, McQuillan, R, Weale, ME, Crouch, DJM, Johansson, A, Aulchenko, Y, Franklin, CS, Polasek, O, Fuchsberger, C, Corvin, A, Hicks, AA, Vitart, V, Hayward, C, Wild, SH, Meitinger, T, van Duijn, CM, Gyllensten, U, Wright, A, Campbell, H, Pramstaller, PP, Rudan, I & Wilson, JF 2010, 'Genes predict village of origin in rural Europe', European Journal of Human Genetics, vol. 18, no. 11, pp. 1269-1270. https://doi.org/10.1038/ejhg.2010.92

TY - JOUR

T1 - Genes predict village of origin in rural Europe

AU - O'Dushlaine, Colm

AU - McQuillan, Ruth

AU - Weale, Michael E.

AU - Crouch, Daniel J. M.

AU - Johansson, Asa

AU - Aulchenko, Yurii

AU - Franklin, Christopher S.

AU - Polasek, Ozren

AU - Fuchsberger, Christian

AU - Corvin, Aiden

AU - Hicks, Andrew A.

AU - Vitart, Veronique

AU - Hayward, Caroline

AU - Wild, Sarah H.

AU - Meitinger, Thomas

AU - van Duijn, Cornelia M.

AU - Gyllensten, Ulf

AU - Wright, Alan

AU - Campbell, Harry

AU - Pramstaller, Peter P.

AU - Rudan, Igor

AU - Wilson, James F.

PY - 2010/11

Y1 - 2010/11

N2 - The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010

AB - The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010

KW - population structure

KW - principal components

KW - genome-wide genotyping

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U2 - 10.1038/ejhg.2010.92

DO - 10.1038/ejhg.2010.92

M3 - Article

C2 - 20571506

SN - 1018-4813

VL - 18

SP - 1269

EP - 1270

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

IS - 11

ER -

Genes predict village of origin in rural Europe

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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