Genetic background of early life telomere length and association with dairy cow longevity

Joanna Ilska, Androniki Psifidi, Luise Seeker, Christopher Whitelaw, M. Coffey, Daniel Nussey, Georgios Banos

Research output: Contribution to conferencePaperpeer-review

Abstract / Description of output

Involuntary culling is a major cause of economic loss in dairy cows. Here we examine the genetic background of telomere length (TL) and its association with dairy cow longevity, using the largest dataset of TL measurement in livestock species. Heritability of TL at birth (TLB) was moderate and significant. A genome-wide association study (GWAS) revealed three suggestive genome-wide significant SNPs on chromosomes 1 and 23 affecting TLB. Significant phenotypic correlations of TLB with a range of longevity traits and a significant genetic correlation with survival to 48 months of age were also estimated. Keywords: longevity, dairy, telomere length, biomarker, GWAS
Original languageEnglish
Publication statusPublished - 11 Feb 2018
Event11th World Congress on Genetics Applied to Livestock Production - Aotea Centre, Auckland, New Zealand
Duration: 11 Feb 201816 Feb 2018

Conference

Conference11th World Congress on Genetics Applied to Livestock Production
Abbreviated titleWCGALP
Country/TerritoryNew Zealand
CityAuckland
Period11/02/1816/02/18

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