Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects

Lavinia Paternoster, Nahara A Martinez-Gonzalez, Rebecca Charleton, Mabel Chung, Stephanie Lewis, Cathie L M Sudlow

Research output: Contribution to journalArticlepeer-review

Abstract

Carotid intima-media thickness (CIMT) is highly heritable and associated with stroke and myocardial infarction, making it a promising quantitative intermediate phenotype for genetic studies of vascular disease. There have been many CIMT candidate gene association studies, but no systematic review to identify consistent, reliable findings.
Original languageEnglish
Pages (from-to)15-21
Number of pages7
JournalCirculation: Cardiovascular Genetics
Volume3
Issue number1
DOIs
Publication statusPublished - 2010

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