Genetics and molecular biology of mouse pigmentation

Ian Jackson, P Budd, J M Horn, R Johnson, S Raymond, K Steel

Research output: Contribution to journalLiterature reviewpeer-review

Abstract

The formation of mouse coat color is a relatively complex developmental process that is affected by a large number of mutations, both naturally occurring and induced. The cloning of the genes in which these mutations occur and the elucidation of the mechanisms by which these mutations disrupt the normal pigmentation pattern is leading to an understanding of the way interactions between gene products lead to a final phenotype.
Original languageEnglish
Pages (from-to)73-80
Number of pages8
JournalPigment cell research
Volume7
Issue number2
Publication statusPublished - Apr 1994

Keywords

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Humans
  • Intramolecular Oxidoreductases
  • Isomerases/genetics
  • Melanocytes/physiology
  • Membrane Glycoproteins
  • Mice
  • Molecular Sequence Data
  • Monophenol Monooxygenase/genetics
  • Oxidoreductases
  • Pigmentation/genetics
  • Proteins/genetics

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