Genome-wide association and genomic prediction of resistance to viral nervous necrosis in European sea bass (Dicentrarchus labrax) using RAD sequencing

Christos Palaiokostas, Sophie Cariou, Anastasia Bestin, Jean-Sebastion Bruant, Thierry Morin, Joelle Cabon, Francois Allal, Marc Vandeputte, Ross Houston

Research output: Contribution to journalArticlepeer-review

Abstract

European sea bass (Dicentrarchus labrax) is one of the most important species for European aquaculture. Viral nervous necrosis (VNN), commonly caused by the redspotted grouper nervous necrosis virus (RGNNV), can result in high levels of morbidity and mortality, mainly during the larval and juvenile stages of cultured sea bass. In the absence of efficient therapeutic treatments, selective breeding for host resistance offers a promising strategy to control this disease. Our study aimed at investigating genetic resistance to VNN and genomic-based approaches to improve disease resistance by selective breeding. A population of 1538 sea bass juveniles from a factorial cross between 48 sires and 17 dams was challenged with RGNNV with mortalities and survivors being recorded and sampled for genotyping by the RAD sequencing approach.
Original languageEnglish
Article number30
JournalGenetics Selection Evolution
Volume50
Issue number1
DOIs
Publication statusPublished - 8 Jun 2018

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