Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Lasse Folkersen; Stefan Gustafsson; Qin Wang; Daniel Hvidberg  Hansen; Asa K Hedman; Andre W  Schork; Karen Page; Daria V Zhernakova; Yang Wu; James Peters; Niclas Eriksson; Sarah E. Bergen; Thibaud Boutin; Andrew D Bretherick; Stefan Enroth; Anette Kalnapenkis; Jesper R Gådin; Bianca Suur; Yan Chen; Ljubica  Matic; Jeremy D  Gale; Julie Lee; Weidong  Zhang; Amira Quazi; Mika Ala-Korpela; Seung Hoan Choi; Annique Claringbould; John Danesh; George  Davey Smith; Federic o de Masi; Solve Elmståhl; Gunnar Engström; Eric Fauman; Celine Fernandez; Lude Franke; Paul Franks; Vilmantas Giedraitis; Chris Haley; Caroline Hayward; James F Wilson; Lars Wallentin; Adam S Butterworth; Michael V Holmes; Erik Ingelsson; Anders Mälarstig

doi:https://doi.org/10.1038/s42255-020-00287-2

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Lasse Folkersen, Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Asa K Hedman, Andre W Schork, Karen Page, Daria V Zhernakova, Yang Wu, James Peters, Niclas Eriksson, Sarah E. Bergen, Thibaud Boutin, Andrew D Bretherick, Stefan Enroth, Anette Kalnapenkis, Jesper R Gådin, Bianca Suur, Yan Chen, Ljubica MaticJeremy D Gale, Julie Lee, Weidong Zhang, Amira Quazi, Mika Ala-Korpela, Seung Hoan Choi, Annique Claringbould, John Danesh, George Davey Smith, Federic o de Masi, Solve Elmståhl, Gunnar Engström, Eric Fauman, Celine Fernandez, Lude Franke, Paul Franks, Vilmantas Giedraitis, Chris Haley, Caroline Hayward, James F Wilson, Lars Wallentin, Adam S Butterworth, Michael V Holmes, Erik Ingelsson, Anders Mälarstig

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Nature Metabolism
Early online date	16 Oct 2020
DOIs	https://doi.org/10.1038/s42255-020-00287-2
Publication status	E-pub ahead of print - 16 Oct 2020

Access to Document

https://doi.org/10.1038/s42255-020-00287-2

Genomic evaluation of circulating proteins for drug target characterisation and precision medicineAccepted author manuscript, 4.25 MB

Andrew Bretherick
- MRC Human Genetics Unit
- Deanery of Molecular, Genetic and Population Health Sciences - Senior Clinical Research Fellow in Anaesthetics
Person: Academic: Research Active

Cite this

Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, A. K., Schork, A. W., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B., Chen, Y., ... Mälarstig, A. (2020). Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nature Metabolism. Advance online publication. https://doi.org/10.1038/s42255-020-00287-2

@article{76a3d95b3b0144159b56b56f09201fd4,

title = "Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals",

author = "Lasse Folkersen and Stefan Gustafsson and Qin Wang and Hansen, {Daniel Hvidberg} and Hedman, {Asa K} and Schork, {Andre W} and Karen Page and Zhernakova, {Daria V} and Yang Wu and James Peters and Niclas Eriksson and Bergen, {Sarah E.} and Thibaud Boutin and Bretherick, {Andrew D} and Stefan Enroth and Anette Kalnapenkis and G{\aa}din, {Jesper R} and Bianca Suur and Yan Chen and Ljubica Matic and Gale, {Jeremy D} and Julie Lee and Weidong Zhang and Amira Quazi and Mika Ala-Korpela and Choi, {Seung Hoan} and Annique Claringbould and John Danesh and {Davey Smith}, George and {o de Masi}, Federic and Solve Elmst{\aa}hl and Gunnar Engstr{\"o}m and Eric Fauman and Celine Fernandez and Lude Franke and Paul Franks and Vilmantas Giedraitis and Chris Haley and Caroline Hayward and Wilson, {James F} and Lars Wallentin and Butterworth, {Adam S} and Holmes, {Michael V} and Erik Ingelsson and Anders M{\"a}larstig",

year = "2020",

month = oct,

day = "16",

doi = "https://doi.org/10.1038/s42255-020-00287-2",

language = "English",

journal = "Nature Metabolism",

issn = "2522-5812",

publisher = "Springer",

}

Folkersen, L, Gustafsson, S, Wang, Q, Hansen, DH, Hedman, AK, Schork, AW, Page, K, Zhernakova, DV, Wu, Y, Peters, J, Eriksson, N, Bergen, SE, Boutin, T , Bretherick, AD, Enroth, S, Kalnapenkis, A, Gådin, JR, Suur, B, Chen, Y, Matic, L, Gale, JD, Lee, J, Zhang, W, Quazi, A, Ala-Korpela, M, Choi, SH, Claringbould, A, Danesh, J, Davey Smith, G, o de Masi, F, Elmståhl, S, Engström, G, Fauman, E, Fernandez, C, Franke, L, Franks, P, Giedraitis, V, Haley, C , Hayward, C , Wilson, JF, Wallentin, L, Butterworth, AS, Holmes, MV, Ingelsson, E & Mälarstig, A 2020, 'Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals', Nature Metabolism. https://doi.org/10.1038/s42255-020-00287-2

TY - JOUR

T1 - Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

AU - Folkersen, Lasse

AU - Gustafsson, Stefan

AU - Wang, Qin

AU - Hansen, Daniel Hvidberg

AU - Hedman, Asa K

AU - Schork, Andre W

AU - Page, Karen

AU - Zhernakova, Daria V

AU - Wu, Yang

AU - Peters, James

AU - Eriksson, Niclas

AU - Bergen, Sarah E.

AU - Boutin, Thibaud

AU - Bretherick, Andrew D

AU - Enroth, Stefan

AU - Kalnapenkis, Anette

AU - Gådin, Jesper R

AU - Suur, Bianca

AU - Chen, Yan

AU - Matic, Ljubica

AU - Gale, Jeremy D

AU - Lee, Julie

AU - Zhang, Weidong

AU - Quazi, Amira

AU - Ala-Korpela, Mika

AU - Choi, Seung Hoan

AU - Claringbould, Annique

AU - Danesh, John

AU - Davey Smith, George

AU - o de Masi, Federic

AU - Elmståhl, Solve

AU - Engström, Gunnar

AU - Fauman, Eric

AU - Fernandez, Celine

AU - Franke, Lude

AU - Franks, Paul

AU - Giedraitis, Vilmantas

AU - Haley, Chris

AU - Hayward, Caroline

AU - Wilson, James F

AU - Wallentin, Lars

AU - Butterworth, Adam S

AU - Holmes, Michael V

AU - Ingelsson, Erik

AU - Mälarstig, Anders

PY - 2020/10/16

Y1 - 2020/10/16

U2 - https://doi.org/10.1038/s42255-020-00287-2

DO - https://doi.org/10.1038/s42255-020-00287-2

M3 - Article

SN - 2522-5812

JO - Nature Metabolism

JF - Nature Metabolism

ER -

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Access to Document

Profiles

Andrew Bretherick

Cite this