Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Lasse Folkersen; Stefan Gustafsson; Qin Wang; Daniel Hvidberg  Hansen; Asa K Hedman; Andre W  Schork; Karen Page; Daria V Zhernakova; Yang Wu; James Peters; Niclas Eriksson; Sarah E. Bergen; Thibaud Boutin; Andrew D Bretherick; Stefan Enroth; Anette Kalnapenkis; Jesper R Gådin; Bianca Suur; Yan Chen; Ljubica  Matic; Jeremy D  Gale; Julie Lee; Weidong  Zhang; Amira Quazi; Mika Ala-Korpela; Seung Hoan Choi; Annique Claringbould; John Danesh; George  Davey Smith; Federic o de Masi; Solve Elmståhl; Gunnar Engström; Eric Fauman; Celine Fernandez; Lude Franke; Paul Franks; Vilmantas Giedraitis; Chris Haley; Caroline Hayward; James F Wilson; Lars Wallentin; Adam S Butterworth; Michael V Holmes; Erik Ingelsson; Anders Mälarstig

doi:10.1038/s42255-020-00287-2

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Lasse Folkersen, Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Asa K Hedman, Andre W Schork, Karen Page, Daria V Zhernakova, Yang Wu, James Peters, Niclas Eriksson, Sarah E. Bergen, Thibaud Boutin, Andrew D Bretherick, Stefan Enroth, Anette Kalnapenkis, Jesper R Gådin, Bianca Suur, Yan Chen, Ljubica MaticJeremy D Gale, Julie Lee, Weidong Zhang, Amira Quazi, Mika Ala-Korpela, Seung Hoan Choi, Annique Claringbould, John Danesh, George Davey Smith, Federic o de Masi, Solve Elmståhl, Gunnar Engström, Eric Fauman, Celine Fernandez, Lude Franke, Paul Franks, Vilmantas Giedraitis, Chris Haley, Caroline Hayward, James F Wilson, Lars Wallentin, Adam S Butterworth, Michael V Holmes, Erik Ingelsson, Anders Mälarstig

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Nature Metabolism
Early online date	16 Oct 2020
DOIs	https://doi.org/10.1038/s42255-020-00287-2
Publication status	E-pub ahead of print - 16 Oct 2020

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10.1038/s42255-020-00287-2

Genomic evaluation of circulating proteins for drug target characterisation and precision medicineAccepted author manuscript, 4.25 MB

Andrew Bretherick
- MRC Human Genetics Unit
- Institute of Genetics and Cancer - Senior Clinical Research Fellow in Anaesthetics
Person: Academic: Research Active

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Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, A. K., Schork, A. W., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B., Chen, Y., ... Mälarstig, A. (2020). Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nature Metabolism. Advance online publication. https://doi.org/10.1038/s42255-020-00287-2

@article{76a3d95b3b0144159b56b56f09201fd4,

title = "Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals",

author = "Lasse Folkersen and Stefan Gustafsson and Qin Wang and Hansen, \{Daniel Hvidberg\} and Hedman, \{Asa K\} and Schork, \{Andre W\} and Karen Page and Zhernakova, \{Daria V\} and Yang Wu and James Peters and Niclas Eriksson and Bergen, \{Sarah E.\} and Thibaud Boutin and Bretherick, \{Andrew D\} and Stefan Enroth and Anette Kalnapenkis and G{\aa}din, \{Jesper R\} and Bianca Suur and Yan Chen and Ljubica Matic and Gale, \{Jeremy D\} and Julie Lee and Weidong Zhang and Amira Quazi and Mika Ala-Korpela and Choi, \{Seung Hoan\} and Annique Claringbould and John Danesh and \{Davey Smith\}, George and \{o de Masi\}, Federic and Solve Elmst{\aa}hl and Gunnar Engstr{\"o}m and Eric Fauman and Celine Fernandez and Lude Franke and Paul Franks and Vilmantas Giedraitis and Chris Haley and Caroline Hayward and Wilson, \{James F\} and Lars Wallentin and Butterworth, \{Adam S\} and Holmes, \{Michael V\} and Erik Ingelsson and Anders M{\"a}larstig",

year = "2020",

month = oct,

day = "16",

doi = "10.1038/s42255-020-00287-2",

language = "English",

journal = "Nature Metabolism",

issn = "2522-5812",

publisher = "Springer",

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Folkersen, L, Gustafsson, S, Wang, Q, Hansen, DH, Hedman, AK, Schork, AW, Page, K, Zhernakova, DV, Wu, Y, Peters, J, Eriksson, N, Bergen, SE, Boutin, T, Bretherick, AD, Enroth, S, Kalnapenkis, A, Gådin, JR, Suur, B, Chen, Y, Matic, L, Gale, JD, Lee, J, Zhang, W, Quazi, A, Ala-Korpela, M, Choi, SH, Claringbould, A, Danesh, J, Davey Smith, G, o de Masi, F, Elmståhl, S, Engström, G, Fauman, E, Fernandez, C, Franke, L, Franks, P, Giedraitis, V, Haley, C, Hayward, C , Wilson, JF, Wallentin, L, Butterworth, AS, Holmes, MV, Ingelsson, E & Mälarstig, A 2020, 'Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals', Nature Metabolism. https://doi.org/10.1038/s42255-020-00287-2

TY - JOUR

T1 - Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

AU - Folkersen, Lasse

AU - Gustafsson, Stefan

AU - Wang, Qin

AU - Hansen, Daniel Hvidberg

AU - Hedman, Asa K

AU - Schork, Andre W

AU - Page, Karen

AU - Zhernakova, Daria V

AU - Wu, Yang

AU - Peters, James

AU - Eriksson, Niclas

AU - Bergen, Sarah E.

AU - Boutin, Thibaud

AU - Bretherick, Andrew D

AU - Enroth, Stefan

AU - Kalnapenkis, Anette

AU - Gådin, Jesper R

AU - Suur, Bianca

AU - Chen, Yan

AU - Matic, Ljubica

AU - Gale, Jeremy D

AU - Lee, Julie

AU - Zhang, Weidong

AU - Quazi, Amira

AU - Ala-Korpela, Mika

AU - Choi, Seung Hoan

AU - Claringbould, Annique

AU - Danesh, John

AU - Davey Smith, George

AU - o de Masi, Federic

AU - Elmståhl, Solve

AU - Engström, Gunnar

AU - Fauman, Eric

AU - Fernandez, Celine

AU - Franke, Lude

AU - Franks, Paul

AU - Giedraitis, Vilmantas

AU - Haley, Chris

AU - Hayward, Caroline

AU - Wilson, James F

AU - Wallentin, Lars

AU - Butterworth, Adam S

AU - Holmes, Michael V

AU - Ingelsson, Erik

AU - Mälarstig, Anders

PY - 2020/10/16

Y1 - 2020/10/16

U2 - 10.1038/s42255-020-00287-2

DO - 10.1038/s42255-020-00287-2

M3 - Article

SN - 2522-5812

JO - Nature Metabolism

JF - Nature Metabolism

ER -

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

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Andrew Bretherick

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