Projects per year
Abstract / Description of output
This paper considers the application of genetic and genomic techniques to disease resistance, the interpretation of data arising from such studies and the utilisation of the research outcomes to breed animals for enhanced resistance. Resistance and tolerance are defined and contrasted, factors affecting the analysis and interpretation of field data presented, and appropriate experimental designs discussed. These general principles are then applied to two detailed case studies, infectious pancreatic necrosis in Atlantic salmon and bovine tuberculosis in dairy cattle, and the lessons learnt are considered in detail. It is concluded that the rate limiting step in disease genetic studies will generally be provision of adequate phenotypic data, and its interpretation, rather than the genomic resources. Lastly, the importance of cross-disciplinary dialogue between the animal health and animal genetics communities is stressed.
Original language | English |
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Pages (from-to) | 190-198 |
Journal | Livestock Science |
Volume | 166 |
Issue number | Sp. Iss. 1 |
Early online date | 14 May 2014 |
DOIs | |
Publication status | Published - 2014 |
Keywords / Materials (for Non-textual outputs)
- Genetics Epidemiology Infection Tolerance Infectious pancreatic necrosis Bovine tuberculosis
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Dive into the research topics of 'Genomics and disease resistance studies in livestock'. Together they form a unique fingerprint.Projects
- 10 Finished
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Mapping and functional characterisation of the Atlantic salmon genome and itsregulation of pathogen response
Houston, R.
1/08/14 → 30/12/14
Project: Research
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Genomic Selection for Bovine Tuberculosis Resistance in Dairy cows
Glass, E., Bishop, S. & Woolliams, J.
24/03/14 → 23/09/17
Project: Research
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Geogios Banos: Development of national genetic evaluations for bovine tuberculosis resistance
Banos, G., Bishop, S. & Woolliams, J.
1/07/13 → 31/01/15
Project: Research