Genotype-phenotype correlation of mouse pde6b mutations

Alan Hart, Lisa McKie, Joanne E Morgan, Philippe Gautier, Katrine West, Ian J Jackson, Sally H Cross

Research output: Contribution to journalArticlepeer-review

Abstract

To identify the underlying molecular defects causing retinal degeneration in seven N-ethyl-N-nitrosourea (ENU) induced mutant alleles of the Pde6b gene and to analyze the timescale of retinal degeneration in these new models of retinitis pigmentosa.
Original languageEnglish
Pages (from-to)3443-50
Number of pages8
Journal Investigative Ophthalmology & Visual Science (IOVS)
Volume46
Issue number9
DOIs
Publication statusPublished - 2005

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