Abstract
We describe GIFT [for GldG, intraflagellar transport (IFT)] domains in the flavobacterial gliding protein GldG and eukaryotic IFT-52. In eukaryotes, domain homologues are also found in the eukaryotic oligosaccharyltransferase complex and in subtilisin kexin isozyme-1 (SKI-1 or S1P). A distant evolutionary relationship to periplasmic-binding proteins hints that GIFT domains might possess oligosaccharide-binding functions.
Original language | English |
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Pages (from-to) | 396-9 |
Number of pages | 4 |
Journal | Trends in biochemical sciences |
Volume | 29 |
Issue number | 8 |
DOIs | |
Publication status | Published - Aug 2004 |
Keywords / Materials (for Non-textual outputs)
- Algal Proteins
- Amino Acid Sequence
- Animals
- Bacterial Proteins
- Biological Evolution
- Eukaryotic Cells
- Flagella
- Flavobacterium
- Glycosylation
- Molecular Sequence Data
- Oligosaccharides
- Proprotein Convertases
- Protein Structure, Tertiary
- Protein Transport
- Protozoan Proteins
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid