Going mobile: Non-cell-autonomous small RNAs shape the genetic landscape of plants

Douglas E. Pyott; Attila Molnar

doi:10.1111/pbi.12353

Going mobile: Non-cell-autonomous small RNAs shape the genetic landscape of plants

Douglas E. Pyott, Attila Molnar^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

RNA silencing is a form of genetic regulation, which is conserved across eukaryotes and has wide ranging biological functions. Recently, there has been a growing appreciation for the importance of mobility in RNA silencing pathways, particularly in plants. Moreover, in addition to the importance for mobile RNA silencing in an evolutionary context, the potential for utilizing mobile short silencing RNAs in biotechnological applications is becoming apparent. This review aims to set current knowledge of this topic in a historical context and provides examples to illustrate the importance of mobile RNA silencing in both natural and artificially engineered systems in plants.

Original language	English
Pages (from-to)	306-318
Number of pages	13
Journal	Plant biotechnology journal
Volume	13
Issue number	3
DOIs	https://doi.org/10.1111/pbi.12353
Publication status	Published - Apr 2015

Keywords / Materials (for Non-textual outputs)

RNA silencing
miRNA
siRNA
mobility
epigenetics
biotechnology
directed DNA methylation
de-novo methylation
dicer-like proteins
double-stranded-RNA
arabidopsis-thaliana
silencing signal
transposable elements
antiviral defense
pattern-formation
interfering RNAS

Access to Document

10.1111/pbi.12353

EASTBIO: EASTBIO East of Scotland BioScience Doctoral Training Partnership studentship - Research Training Grant BB/J01446X/1
Smith, S. (Student)
1/09/12 → 30/09/18
Project: Other (Non-Funded/Miscellaneous)

Cite this

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title = "Going mobile: Non-cell-autonomous small RNAs shape the genetic landscape of plants",

abstract = "RNA silencing is a form of genetic regulation, which is conserved across eukaryotes and has wide ranging biological functions. Recently, there has been a growing appreciation for the importance of mobility in RNA silencing pathways, particularly in plants. Moreover, in addition to the importance for mobile RNA silencing in an evolutionary context, the potential for utilizing mobile short silencing RNAs in biotechnological applications is becoming apparent. This review aims to set current knowledge of this topic in a historical context and provides examples to illustrate the importance of mobile RNA silencing in both natural and artificially engineered systems in plants.",

keywords = "RNA silencing, miRNA, siRNA, mobility, epigenetics, biotechnology, directed DNA methylation, de-novo methylation, dicer-like proteins, double-stranded-RNA, arabidopsis-thaliana, silencing signal, transposable elements, antiviral defense, pattern-formation, interfering RNAS",

author = "Pyott, {Douglas E.} and Attila Molnar",

year = "2015",

month = apr,

doi = "10.1111/pbi.12353",

language = "English",

volume = "13",

pages = "306--318",

journal = "Plant biotechnology journal",

issn = "1467-7644",

publisher = "Wiley-Blackwell",

number = "3",

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TY - JOUR

T1 - Going mobile

T2 - Non-cell-autonomous small RNAs shape the genetic landscape of plants

AU - Pyott, Douglas E.

AU - Molnar, Attila

PY - 2015/4

Y1 - 2015/4

N2 - RNA silencing is a form of genetic regulation, which is conserved across eukaryotes and has wide ranging biological functions. Recently, there has been a growing appreciation for the importance of mobility in RNA silencing pathways, particularly in plants. Moreover, in addition to the importance for mobile RNA silencing in an evolutionary context, the potential for utilizing mobile short silencing RNAs in biotechnological applications is becoming apparent. This review aims to set current knowledge of this topic in a historical context and provides examples to illustrate the importance of mobile RNA silencing in both natural and artificially engineered systems in plants.

AB - RNA silencing is a form of genetic regulation, which is conserved across eukaryotes and has wide ranging biological functions. Recently, there has been a growing appreciation for the importance of mobility in RNA silencing pathways, particularly in plants. Moreover, in addition to the importance for mobile RNA silencing in an evolutionary context, the potential for utilizing mobile short silencing RNAs in biotechnological applications is becoming apparent. This review aims to set current knowledge of this topic in a historical context and provides examples to illustrate the importance of mobile RNA silencing in both natural and artificially engineered systems in plants.

KW - RNA silencing

KW - miRNA

KW - siRNA

KW - mobility

KW - epigenetics

KW - biotechnology

KW - directed DNA methylation

KW - de-novo methylation

KW - dicer-like proteins

KW - double-stranded-RNA

KW - arabidopsis-thaliana

KW - silencing signal

KW - transposable elements

KW - antiviral defense

KW - pattern-formation

KW - interfering RNAS

U2 - 10.1111/pbi.12353

DO - 10.1111/pbi.12353

M3 - Review article

SN - 1467-7644

VL - 13

SP - 306

EP - 318

JO - Plant biotechnology journal

JF - Plant biotechnology journal

IS - 3

ER -

Going mobile: Non-cell-autonomous small RNAs shape the genetic landscape of plants

Abstract

Keywords / Materials (for Non-textual outputs)

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Projects

EASTBIO: EASTBIO East of Scotland BioScience Doctoral Training Partnership studentship - Research Training Grant BB/J01446X/1

Cite this