Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma: resolution following chemotherapy

A J Drake; S P Lowis; E Bouffet; E C Crowne

doi:53188

Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma: resolution following chemotherapy

A J Drake, S P Lowis, E Bouffet, E C Crowne

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Growth hormone hypersecretion is extremely rare in childhood. We report a girl with neurofibromatosis type 1, an extensive optic nerve glioma and growth hormone hypersecretion. She was treated with chemotherapy to prevent further extension of her sight-threatening tumour. Three years after chemotherapy her growth hormone hypersecretion has resolved although she has gone on to develop precocious puberty.

Original language	English
Pages (from-to)	305-8
Number of pages	4
Journal	Hormone Research
Volume	53
Issue number	6
DOIs	https://doi.org/53188
Publication status	Published - 2000

Keywords / Materials (for Non-textual outputs)

Age Determination by Skeleton
Antineoplastic Combined Chemotherapy Protocols
Body Height
Child, Preschool
Dactinomycin
Female
Glioma
Glucose Tolerance Test
Human Growth Hormone
Humans
Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor I
Magnetic Resonance Imaging
Neurofibromatosis 1
Optic Nerve Neoplasms
Prolactin
Puberty, Precocious
Vincristine
Weight Gain

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title = "Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma: resolution following chemotherapy",

abstract = "Growth hormone hypersecretion is extremely rare in childhood. We report a girl with neurofibromatosis type 1, an extensive optic nerve glioma and growth hormone hypersecretion. She was treated with chemotherapy to prevent further extension of her sight-threatening tumour. Three years after chemotherapy her growth hormone hypersecretion has resolved although she has gone on to develop precocious puberty.",

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author = "Drake, {A J} and Lowis, {S P} and E Bouffet and Crowne, {E C}",

year = "2000",

doi = "53188",

language = "English",

volume = "53",

pages = "305--8",

journal = "Hormone Research",

issn = "0301-0163",

publisher = "S. Karger AG",

number = "6",

}

TY - JOUR

T1 - Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma

T2 - resolution following chemotherapy

AU - Drake, A J

AU - Lowis, S P

AU - Bouffet, E

AU - Crowne, E C

PY - 2000

Y1 - 2000

N2 - Growth hormone hypersecretion is extremely rare in childhood. We report a girl with neurofibromatosis type 1, an extensive optic nerve glioma and growth hormone hypersecretion. She was treated with chemotherapy to prevent further extension of her sight-threatening tumour. Three years after chemotherapy her growth hormone hypersecretion has resolved although she has gone on to develop precocious puberty.

AB - Growth hormone hypersecretion is extremely rare in childhood. We report a girl with neurofibromatosis type 1, an extensive optic nerve glioma and growth hormone hypersecretion. She was treated with chemotherapy to prevent further extension of her sight-threatening tumour. Three years after chemotherapy her growth hormone hypersecretion has resolved although she has gone on to develop precocious puberty.

KW - Age Determination by Skeleton

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Body Height

KW - Child, Preschool

KW - Dactinomycin

KW - Female

KW - Glioma

KW - Glucose Tolerance Test

KW - Human Growth Hormone

KW - Humans

KW - Insulin-Like Growth Factor Binding Protein 3

KW - Insulin-Like Growth Factor I

KW - Magnetic Resonance Imaging

KW - Neurofibromatosis 1

KW - Optic Nerve Neoplasms

KW - Prolactin

KW - Puberty, Precocious

KW - Vincristine

KW - Weight Gain

U2 - 53188

DO - 53188

M3 - Article

C2 - 11146372

SN - 0301-0163

VL - 53

SP - 305

EP - 308

JO - Hormone Research

JF - Hormone Research

IS - 6

ER -

Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma: resolution following chemotherapy

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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