Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS (R)) Society recommendations

ERAS Soc, European Soc Clinical Nutr Metab, Int Assoc Surgical Metab, Kristoffer Lassen*, Marielle M. E. Coolsen, Karem Slim, Francesco Carli, Jose E. de Aguilar-Nascimento, Markus Schaefer, Rowan W. Parks, Kenneth C. H. Fearon, Dileep N. Lobo, Nicolas Demartines, Marco Braga, Olle Ljungqvist, Cornelis H. C. Dejong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background & aims: Protocols for enhanced recovery provide comprehensive and evidence-based guidelines for best perioperative care. Protocol implementation may reduce complication rates and enhance functional recovery and, as a result of this, also reduce length-of-stay in hospital. There is no comprehensive framework available for pancreaticoduodenectomy.

Methods: An international working group constructed within the Enhanced Recovery After Surgery (ERAS (R)) Society constructed a comprehensive and evidence-based framework for best perioperative care for pancreaticoduodenectomy patients. Data were retrieved from standard databases and personal archives. Evidence and recommendations were classified according to the GRADE system and reached through consensus in the group. The quality of evidence was rated "high", "moderate", "low" or "very low". Recommendations were graded as "strong" or "weak".

Results: Comprehensive guidelines are presented. Available evidence is summarised and recommendations given for 27 care items. The quality of evidence varies substantially and further research is needed for many issues to improve the strength of evidence and grade of recommendations.

Conclusions: The present evidence-based guidelines provide the necessary platform upon which to base a unified protocol for perioperative care for pancreaticoduodenectomy. A unified protocol allows for comparison between centres and across national borders. It facilitates multi-institutional prospective cohort registries and adequately powered randomised trials. (C) 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Original languageEnglish
Pages (from-to)817-830
Number of pages14
JournalClinical Nutrition
Volume31
Issue number6
DOIs
Publication statusPublished - Dec 2012

Keywords

  • THORACIC EPIDURAL ANALGESIA
  • ELECTIVE COLORECTAL SURGERY
  • PREOPERATIVE BILIARY DRAINAGE
  • Pancreas
  • Guidelines
  • ROUTINE NASOGASTRIC DECOMPRESSION
  • Enhanced Recovery After Surgery (ERAS)
  • RANDOMIZED-CONTROLLED-TRIAL
  • POSTOPERATIVE INSULIN-RESISTANCE
  • SURGICAL SITE INFECTIONS
  • Whipple
  • Pancreatoduodenectomy
  • URINARY-TRACT-INFECTION
  • Fast track
  • CIRCULATING-WATER GARMENT
  • Critical pathway
  • UPPER-GASTROINTESTINAL SURGERY

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