HEMODYNAMIC-EFFECTS OF A SINGLE MODERATE DOSE OF ALCOHOL IN ELDERLY SUBJECTS

DJ STOTT*, M DUTTON, GD MURRAY, BO WILLIAMS, GT MCINNES

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The effects of 0.5 g ethanol/kg body weight and of an iso-volumic control drink were compared in eight normotensive subjects aged 70-96 years. Blood alcohol concentration reached a mean (+/- SEM) maximum of 44.4 +/- 5.0 mg/dl at 50 minutes after the start of drinking. Compared to control, alcohol increased mean sitting and standing heart rates by 3.4 +/- 1.3 (p = .08) and 5.4 +/- 1.9 (p <.05) beats/minute, respectively; mean venous haematocrit rose by 3.9 +/- 1.3% (p <.05). There were no significant changes in sitting or standing systolic or diastolic blood pressures after alcohol compared to the control drink. A single moderate dose of alcohol has only minor haemodynamic effects in normotensive elderly subjects. The rise in heart rate after alcohol may be a reflex response that helps to maintain blood pressure in the face of reduced circulating plasma volume due to alcohol-induced diuresis.

Original languageEnglish
Pages (from-to)377-379
Number of pages3
JournalJournal of studies on alcohol
Volume52
Issue number4
Publication statusPublished - Jul 1991

Keywords

  • BLOOD-PRESSURE
  • ETHANOL
  • BLOCKADE

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