HEMOSTATIC ABNORMALITIES AND OUTCOME IN PATIENTS WITH OPERABLE BREAST-CANCER

P MCCULLOCH; GDO LOWE; JT DOUGLAS; GD MURRAY; WD GEORGE

HEMOSTATIC ABNORMALITIES AND OUTCOME IN PATIENTS WITH OPERABLE BREAST-CANCER

P MCCULLOCH^*, GDO LOWE, JT DOUGLAS, GD MURRAY, WD GEORGE

^*Corresponding author for this work

Deanery of Molecular, Genetic and Population Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

The predictive value for cancer recurrence of five measurements of haemostatic activity was studied in 89 patients with operable breast cancer. Neither preoperative nor sequential measurements up to 9 months postoperatively of fibrinopeptide A, fibrin fragment B-BETA-15-42, fibrinogen and serum fibrin(ogen) degradation products nor the fibrin plate lysis assay correlated with early recurrent disease. B-BETA-15-42 values were higher preoperatively in patients with oestrogen receptor positive tumours (P = 0.017). Mean B-BETA-15-42 values rose postoperatively (P = 0.003), largely because of an increase in patients with oestrogen receptor negative tumours.

Original language	English
Pages (from-to)	950-953
Number of pages	4
Journal	European Journal of Cancer
Volume	26
Issue number	9
Publication status	Published - 1990

Keywords / Materials (for Non-textual outputs)

FIBRINOPEPTIDE-A
MALIGNANT-TISSUE
TUMOR
BLOOD
ANTICOAGULATION
COAGULATION
METASTASIS
CARCINOMA

Cite this

@article{be2adc0a15f9437888775f0bb8abf999,

title = "HEMOSTATIC ABNORMALITIES AND OUTCOME IN PATIENTS WITH OPERABLE BREAST-CANCER",

abstract = "The predictive value for cancer recurrence of five measurements of haemostatic activity was studied in 89 patients with operable breast cancer. Neither preoperative nor sequential measurements up to 9 months postoperatively of fibrinopeptide A, fibrin fragment B-BETA-15-42, fibrinogen and serum fibrin(ogen) degradation products nor the fibrin plate lysis assay correlated with early recurrent disease. B-BETA-15-42 values were higher preoperatively in patients with oestrogen receptor positive tumours (P = 0.017). Mean B-BETA-15-42 values rose postoperatively (P = 0.003), largely because of an increase in patients with oestrogen receptor negative tumours.",

keywords = "FIBRINOPEPTIDE-A, MALIGNANT-TISSUE, TUMOR, BLOOD, ANTICOAGULATION, COAGULATION, METASTASIS, CARCINOMA",

author = "P MCCULLOCH and GDO LOWE and JT DOUGLAS and GD MURRAY and WD GEORGE",

year = "1990",

language = "English",

volume = "26",

pages = "950--953",

journal = "European Journal of Cancer",

issn = "0959-8049",

publisher = "Pergamon Press",

number = "9",

}

TY - JOUR

T1 - HEMOSTATIC ABNORMALITIES AND OUTCOME IN PATIENTS WITH OPERABLE BREAST-CANCER

AU - MCCULLOCH, P

AU - LOWE, GDO

AU - DOUGLAS, JT

AU - MURRAY, GD

AU - GEORGE, WD

PY - 1990

Y1 - 1990

N2 - The predictive value for cancer recurrence of five measurements of haemostatic activity was studied in 89 patients with operable breast cancer. Neither preoperative nor sequential measurements up to 9 months postoperatively of fibrinopeptide A, fibrin fragment B-BETA-15-42, fibrinogen and serum fibrin(ogen) degradation products nor the fibrin plate lysis assay correlated with early recurrent disease. B-BETA-15-42 values were higher preoperatively in patients with oestrogen receptor positive tumours (P = 0.017). Mean B-BETA-15-42 values rose postoperatively (P = 0.003), largely because of an increase in patients with oestrogen receptor negative tumours.

AB - The predictive value for cancer recurrence of five measurements of haemostatic activity was studied in 89 patients with operable breast cancer. Neither preoperative nor sequential measurements up to 9 months postoperatively of fibrinopeptide A, fibrin fragment B-BETA-15-42, fibrinogen and serum fibrin(ogen) degradation products nor the fibrin plate lysis assay correlated with early recurrent disease. B-BETA-15-42 values were higher preoperatively in patients with oestrogen receptor positive tumours (P = 0.017). Mean B-BETA-15-42 values rose postoperatively (P = 0.003), largely because of an increase in patients with oestrogen receptor negative tumours.

KW - FIBRINOPEPTIDE-A

KW - MALIGNANT-TISSUE

KW - TUMOR

KW - BLOOD

KW - ANTICOAGULATION

KW - COAGULATION

KW - METASTASIS

KW - CARCINOMA

M3 - Article

SN - 0959-8049

VL - 26

SP - 950

EP - 953

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 9

ER -

HEMOSTATIC ABNORMALITIES AND OUTCOME IN PATIENTS WITH OPERABLE BREAST-CANCER

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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