A one-year-old, female domestic shorthair cat was referred for ovariohysterectomy with a history of cyanotic mucous membranes for several months. Blood samples exhibited a noticeably brownish blood discoloration, while laboratory screening revealed mild-to-moderate erythrocytosis and near normal partial arterial oxygen pressure. Blood methemoglobin content was 41% of total hemoglobin concentration, and erythrocytic methemoglobin reductase activity was <1% compared with control samples. A diagnosis of hereditary methemoglobinemia was established. After an intravenous injection of methylene blue, the cat’s mucous membranes became transiently pink, and the ovariohysterectomy was uneventfully performed. Methylene blue may have improved safety during anesthesia and surgery.
|Number of pages||502|
|Journal||The Canadian veterinary journal. La revue vétérinaire canadienne|
|Publication status||Published - May 2019|