High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi

Peter Hohenstein, Joan Slight, Derya Deniz Ozdemir, Sally F Burn, Rachel Berry, Nicholas D Hastie

Research output: Contribution to journalArticlepeer-review

Abstract

Rosa26 is a genomic mouse locus commonly used to knock-in cDNA constructs for ubiquitous or conditional gene expression in transgenic mice. However, the vectors generally used to generate Rosa26 knock-in constructs show instability problems, which have a severe impact on the efficiency of the system.
Original languageEnglish
Pages (from-to)3
JournalPathoGenetics
Volume1
Issue number1
DOIs
Publication statusPublished - 2008

Fingerprint Dive into the research topics of 'High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi'. Together they form a unique fingerprint.

Cite this