High frequency microsatellite instability has a prognostic value in endometrial endometrioid adenocarcinoma, but only in FIGO stage 1 cases

Anita Steinbakk, Anais Malpica, Aida Slewa, Einar Gudlaugsson, Emiel A M Janssen, Mark Arends, Arnold Jan Kruse, Yu Yinhua, Weiwei Feng, Jan P Baak

Research output: Contribution to journalArticlepeer-review

Abstract

To analyze the prognostic value of microsatellite instability (MSI) in a population-based study of FIGO stage 1-4 endometrial endometrioid adenocarcinomas. Study Design: Survival analysis in 273 patients of MSI status and clinico-pathologic features. Using a highly sensitive pentaplex polymerase chain reaction to establish MSI status, cases were divided into microsatellite stable (MSS), MSI-low (MSI-L, 1 marker positive) and MSI-high (MSI-H, 2-5 markers positive).
Original languageEnglish
Pages (from-to)457-65
Number of pages9
JournalCellular Oncology
Volume34
Issue number5
DOIs
Publication statusPublished - Oct 2011

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