HippoCA3mpal Stem Cell Models Expose Dysfunctional Circuits in Schizophrenia

Mandy Johnstone, Rana Fetit

Research output: Contribution to journalLiterature review

Abstract / Description of output

In this issue of Cell Stem Cell, Sarkar et al. (2018) describe an efficient method for the generation of human hippocampal pyramidal neurons from stem cells. They developed a compelling in vitro model that recapitulates synaptic connectivity within the hippocampus and showed that cells derived from patients with schizophrenia exhibit abnormal electrical activity.

Original languageEnglish
Pages (from-to)609-611
Number of pages3
JournalCell Stem Cell
Volume22
Issue number5
DOIs
Publication statusPublished - 3 May 2018

Keywords / Materials (for Non-textual outputs)

  • Journal Article

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