HLA B*5701 status, disease progression, and response to antiretroviral therapy

UK Collaborative HIV Cohort Study Steering Committee; Clifford Leen

doi:10.1097/01.aids.0000432613.95455.71

HLA B*5701 status, disease progression, and response to antiretroviral therapy

UK Collaborative HIV Cohort Study Steering Committee, Clifford Leen

College of Medicine and Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

In addition to hypersensitivity reactions to abacavir, HLA B5701 has been associated with slow or nonprogression of HIV infection. We explored the effect of HLA B5701 on CD4 cell count and viral load in untreated patients and on responses to nonabacavir-containing combination antiretroviral therapy (cART) in a large UK-based cohort.

Original language	English
Pages (from-to)	2587-92
Number of pages	6
Journal	AIDS
Volume	27
Issue number	16
DOIs	https://doi.org/10.1097/01.aids.0000432613.95455.71
Publication status	Published - 23 Oct 2013

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title = "HLA B*5701 status, disease progression, and response to antiretroviral therapy",

abstract = "In addition to hypersensitivity reactions to abacavir, HLA B5701 has been associated with slow or nonprogression of HIV infection. We explored the effect of HLA B5701 on CD4 cell count and viral load in untreated patients and on responses to nonabacavir-containing combination antiretroviral therapy (cART) in a large UK-based cohort.",

author = "{UK Collaborative HIV Cohort Study Steering Committee} and Clifford Leen",

year = "2013",

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doi = "10.1097/01.aids.0000432613.95455.71",

language = "English",

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journal = "AIDS",

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publisher = "Lippincott Williams & Wilkins",

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T1 - HLA B*5701 status, disease progression, and response to antiretroviral therapy

AU - UK Collaborative HIV Cohort Study Steering Committee

AU - Leen, Clifford

PY - 2013/10/23

Y1 - 2013/10/23

N2 - In addition to hypersensitivity reactions to abacavir, HLA B5701 has been associated with slow or nonprogression of HIV infection. We explored the effect of HLA B5701 on CD4 cell count and viral load in untreated patients and on responses to nonabacavir-containing combination antiretroviral therapy (cART) in a large UK-based cohort.

AB - In addition to hypersensitivity reactions to abacavir, HLA B5701 has been associated with slow or nonprogression of HIV infection. We explored the effect of HLA B5701 on CD4 cell count and viral load in untreated patients and on responses to nonabacavir-containing combination antiretroviral therapy (cART) in a large UK-based cohort.

U2 - 10.1097/01.aids.0000432613.95455.71

DO - 10.1097/01.aids.0000432613.95455.71

M3 - Article

C2 - 23921616

SN - 0269-9370

VL - 27

SP - 2587

EP - 2592

JO - AIDS

JF - AIDS

IS - 16

ER -

HLA B*5701 status, disease progression, and response to antiretroviral therapy

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