Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium

Diana C Fleming; Anne E King; Alistair R W Williams; Hilary O D Critchley; Rodney W Kelly

Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium

Diana C Fleming, Anne E King, Alistair R W Williams, Hilary O D Critchley, Rodney W Kelly

Research output: Contribution to journal › Article › peer-review

Abstract

To determine the effect of hormonal contraception with a combined oral contraceptive pill and levonorgestrel intrauterine system on the expression of the natural antimicrobials secretory leukocyte protease inhibitor, beta-defensins 1 and 2, and granulysin in human endometrium.

Original language	English
Pages (from-to)	856-63
Number of pages	8
Journal	Fertility and Sterility
Volume	79
Issue number	4
Publication status	Published - Apr 2003

Keywords / Materials (for Non-textual outputs)

Antigens, Differentiation, T-Lymphocyte
Biopsy
Contraceptives, Oral, Combined
Endometrium
Female
Gene Expression Regulation
Humans
Immunohistochemistry
Intrauterine Devices
Levonorgestrel
Menstrual Cycle
Protein Biosynthesis
Proteinase Inhibitory Proteins, Secretory
Proteins
RNA
Reverse Transcriptase Polymerase Chain Reaction
Transcription, Genetic
beta-Defensins

Cite this

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title = "Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium",

abstract = "To determine the effect of hormonal contraception with a combined oral contraceptive pill and levonorgestrel intrauterine system on the expression of the natural antimicrobials secretory leukocyte protease inhibitor, beta-defensins 1 and 2, and granulysin in human endometrium.",

keywords = "Antigens, Differentiation, T-Lymphocyte, Biopsy, Contraceptives, Oral, Combined, Endometrium, Female, Gene Expression Regulation, Humans, Immunohistochemistry, Intrauterine Devices, Levonorgestrel, Menstrual Cycle, Protein Biosynthesis, Proteinase Inhibitory Proteins, Secretory, Proteins, RNA, Reverse Transcriptase Polymerase Chain Reaction, Transcription, Genetic, beta-Defensins",

author = "Fleming, \{Diana C\} and King, \{Anne E\} and Williams, \{Alistair R W\} and Critchley, \{Hilary O D\} and Kelly, \{Rodney W\}",

year = "2003",

month = apr,

language = "English",

volume = "79",

pages = "856--63",

journal = "Fertility and Sterility",

issn = "0015-0282",

publisher = "Elsevier",

number = "4",

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TY - JOUR

T1 - Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium

AU - Fleming, Diana C

AU - King, Anne E

AU - Williams, Alistair R W

AU - Critchley, Hilary O D

AU - Kelly, Rodney W

PY - 2003/4

Y1 - 2003/4

N2 - To determine the effect of hormonal contraception with a combined oral contraceptive pill and levonorgestrel intrauterine system on the expression of the natural antimicrobials secretory leukocyte protease inhibitor, beta-defensins 1 and 2, and granulysin in human endometrium.

AB - To determine the effect of hormonal contraception with a combined oral contraceptive pill and levonorgestrel intrauterine system on the expression of the natural antimicrobials secretory leukocyte protease inhibitor, beta-defensins 1 and 2, and granulysin in human endometrium.

KW - Antigens, Differentiation, T-Lymphocyte

KW - Biopsy

KW - Contraceptives, Oral, Combined

KW - Endometrium

KW - Female

KW - Gene Expression Regulation

KW - Humans

KW - Immunohistochemistry

KW - Intrauterine Devices

KW - Levonorgestrel

KW - Menstrual Cycle

KW - Protein Biosynthesis

KW - Proteinase Inhibitory Proteins, Secretory

KW - Proteins

KW - RNA

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Transcription, Genetic

KW - beta-Defensins

M3 - Article

C2 - 12749421

SN - 0015-0282

VL - 79

SP - 856

EP - 863

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 4

ER -

Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium

Abstract

Keywords / Materials (for Non-textual outputs)

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